Scientists have designed gold nanoparticles, no bigger than 100 nanometres, which can be coated and used to track blood flow in the smallest blood vessels in the body.
By improving our understanding of blood flow in vivo the nanoprobes represent an opportunity to help in the early diagnosis of disease.
Light microscopy is a rapidly evolving field for understanding in vivo systems where high resolution is required. It is particularly crucial for cardiovascular research, where clinical studies are based on ultrasound technologies which inherently have lower resolution and provide limited information.
The ability to monitor blood flow in the sophisticated vascular tree (notably in the smallest elements of the microvasculature – capillaries) can provide invaluable information to understand disease processes such as thrombosis and vascular inflammation. There are further applications for the improved delivery of therapeutics, such as targeting tumours.
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RNA-seq outperforms DNA methods in detecting actionable cancer mutations
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Physicists discover new state of quantum matter
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New research identifies critical gene for treatment
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DNA Nanoflower Targets Breast Cancer Cells in Drug Delivery Breakthrough
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New method genetically blocks mosquitoes from transmitting malaria
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Novel Sonication Method Creates Realistic Nanoplastics for Pollution Research
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Old chemistry unlocks safer and stronger mRNA delivery
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New mRNA vaccine strategy awakens immune system to fight cancer
An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake [...]
Specially engineered antibody delivers RNA therapy to treatment-resistant tumors
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New Cancer Drug Blocks Tumors Without Debilitating Side Effects
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Why ‘Peniaphobia’ Is Exploding Among Young People (And Why We Should Be Concerned)
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Team finds flawed data in recent study relevant to coronavirus antiviral development
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Drug-Coated Neural Implants Reduce Immune Rejection
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Johns Hopkins Researchers Uncover a New Way To Kill Cancer Cells
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AI matches doctors in mapping lung tumors for radiation therapy
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AI tool detects 9 types of dementia from a single brain scan
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AI and nanomedicine find rare biomarkers for prostrate cancer and atherosclerosis
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Are Pesticides Breeding the Next Pandemic? Experts Warn of Fungal Superbugs
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Scientists Crack the 500-Million-Year-Old Code That Controls Your Immune System
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Team discovers how tiny parts of cells stay organized, new insights for blocking cancer growth
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Natural Plant Extract Removes up to 90% of Microplastics From Water
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Instant coffee may damage your eyes, genetic study finds
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Small antibodies provide broad protection against SARS coronaviruses
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Prime Editing: The Next Frontier in Genetic Medicine
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Scientists discover single cell creatures can learn new behaviours
It was previously thought that learning behaviours only applied to animals with complex brain and nervous systems, but a new study has proven that this may also occur in individual cells. As a result, this [...]
Virus which ’causes multiple organ failure’ found at popular Spanish holiday destination
British tourists planning trips to Spain have been warned after a deadly virus that can cause multiple organ failure has been detected in the country. The Foreign Office issued the alert [...]
Urgent health warning as dangerous new Covid virus from China triggers US outbreak
A dangerous new Covid variant from China is surging in California, health officials warn. The California Department of Public Health warned this week the highly contagious NB.1.8.1 strain has been detected in [...]
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Inhalable Nanovaccines: The Future of Needle-Free Immunization
The COVID-19 pandemic highlighted the need for adaptable and scalable vaccine technologies. While mRNA vaccines have improved disease prevention, most are delivered by intramuscular injection, which may not effectively [...]
‘Stealthy’ lipid nanoparticles give mRNA vaccines a makeover
A new material developed at Cornell University could significantly improve the delivery and effectiveness of mRNA vaccines by replacing a commonly used ingredient that may trigger unwanted immune responses [...]
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Experts explain how H5 avian influenza adapts to infect more animals
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3D-printed device enables precise modeling of complex human tissues in the lab
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Ancient DNA sheds light on evolution of relapsing fever bacteria
Researchers at the Francis Crick Institute and UCL have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through [...]
Cold Sore Virus Linked to Alzheimer’s, Antivirals May Lower Risk
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Nanoparticle-Based Combination Therapy for Resistant Melanoma
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Our DNA May Evolve Much Faster Than Previously Thought
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Global life expectancy plunges as WHO warns of deepening health crisis Post-COVID
The World Health Organization (WHO) has sounded the alarm on the long-term health repercussions of the COVID-19 pandemic in its newly released World Health Statistics Report 2025. The report reveals [...]
Researchers map brain networks involved in word retrieval
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Melting Ice Is Changing the Color of the Ocean – Scientists Are Alarmed
Melting sea ice changes not only how much light enters the ocean, but also its color, disrupting marine photosynthesis and altering Arctic ecosystems in subtle but profound ways. As global warming [...]
Your Washing Machine Might Be Helping Antibiotic-Resistant Bacteria Spread
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Scientists Discover Hidden Cause of Alzheimer’s Hiding in Plain Sight
Researchers found the PHGDH gene directly causes Alzheimer’s and discovered a drug-like molecule, NCT-503, that may help treat the disease early by targeting the gene’s hidden function. A recent study has [...]
How Brain Cells Talk: Inside the Complex Language of the Human Mind
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Oxford study reveals how COVID-19 vaccines prevent severe illness
A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated. [...]
Annual blood test could detect cancer earlier and save lives
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How the FDA opens the door to risky chemicals in America’s food supply
Lining the shelves of American supermarkets are food products with chemicals linked to health concerns. To a great extent, the FDA allows food companies to determine for themselves whether [...]
Superbug crisis could get worse, killing nearly 40 million people by 2050
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How Can Nanomaterials Be Programmed for Different Applications?
Nanomaterials are no longer just small—they are becoming smart. Across fields like medicine, electronics, energy, and materials science, researchers are now programming nanomaterials to behave in intentional, responsive ways. [...]
Microplastics Are Invading Our Arteries, and It Could Be Increasing Your Risk of Stroke
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Gene-editing therapy shows early success in fighting advanced gastrointestinal cancers
Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers. The results, [...]
Engineered extracellular vesicles facilitate delivery of advanced medicines
Graphic abstract of the development of VEDIC and VFIC systems for high efficiency intracellular protein delivery in vitro and in vivo. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-59377-y. https://www.nature.com/articles/s41467-025-59377-y Researchers at Karolinska [...]
Brain-computer interface allows paralyzed users to customize their sense of touch
University of Pittsburgh School of Medicine scientists are one step closer to developing a brain-computer interface, or BCI, that allows people with tetraplegia to restore their lost sense of [...]
Scientists Flip a Gut Virus “Kill Switch” – Expose a Hidden Threat in Antibiotic Treatment
Scientists have long known that bacteriophages, viruses that infect bacteria, live in our gut, but exactly what they do has remained elusive. Researchers developed a clever mouse model that [...]
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