Researchers at Aalto University, Finland, have developed a biosensor that enables creating a range of new easy-to-use health tests similar to home pregnancy tests (Advanced Materials, “Plasmonic Metaparticles on a Blackbody Create Vivid Reflective Colors for Naked-eye Environmental- and Clinical Bio-detection”). The plasmonic biosensor can detect diseased exosomes even by the naked eye. Exosomes, important indicators of health conditions, are cell-derived vesicles that are present in blood and urine.
A rapid analysis by biosensors helps recognize inflammatory bowel diseases, cancer and other diseases rapidly and start relevant treatments in time. In addition to using discovery in biomedicine, industry may use advanced applications in energy.
Researchers created a new biosensor by depositing plasmonic metaparticles on a black, physical body that absorbs all incident electromagnetic radiation. A plasmon is a quantum of plasma oscillation. Plasmonic materials have been used for making objects invisible in scientific tests. They efficiently reflect and absorb light. Plasmonic materials are based on the effective polarizabilities of metallic nanostructures.
“It is extraordinary that we can detect diseased exosomes by the naked eye. The conventional plasmonic biosensors are able to detect analytes solely at a molecular level. So far, the naked-eye detection of biosamples has been either rarely considered or unsuccessful”, says Professor Mady Elbahri from Aalto University.