For the very first time in Russia, researchers from NUST MISIS have developed a novel therapeutic material based on nanofibers. The nanofibers are composed of polycaprolactone altered with plasma components of human blood and a thin-film antibacterial composition. The living biodegradable bandages developed from these nanofibers will speed up the growth of tissue cells by twofold. This will play a role in the normal regeneration of damaged tissue cells and also inhibit the formation of scars in cases of major burn injuries.
The key objectives in regenerative medicine, and especially in burn therapy, are the effective regeneration of damaged skin tissue and the prevention of scar formation. When skin is severely damaged, whether through a burn, cut, or a skin problem such as fungal acne infection or acne, it results in scar formation.
Since scar tissue has reduced functional properties, it considerably differs from the tissue it substitutes. Also, since scar primarily mainly contains irreversible collagen. For instance, scars formed on the skin are not elastic, are more susceptible to ultraviolet radiation, and the hair follicles and sweat glands are not restored in the area.
Led by senior researcher Ph.D. Anton Manakhov, a team of researchers from NUST MISIS Inorganic Nanomaterials Laboratory suggested an innovative answer to the medical problem. By creating ‘bandages’ with multi-layers of multifunctional bioactive nanofilms and biodegradable fibers, it helps to stop scarring and speed up new tissue growth.