Mental health services around the world are stretched thinner than ever. Long wait times, barriers to accessing care and rising rates of depression and anxiety have made it harder for people to get timely help.
As a result, governments and health care providers are looking for new ways to address this problem. One emerging solution is the use of AI chatbots for mental health care.
A recent study explored whether a new type of AI chatbot, named Therabot, could treat people with mental illness effectively. The findings were promising: not only did participants with clinically significant symptoms of depression and anxiety benefit, those at high-risk for eating disorders also showed improvement. While early, this study may represent a pivotal moment in the integration of AI into mental health care.
AI mental health chatbots are not new—tools like Woebot and Wysa have already been released to the public and studied for years. These platforms follow rules based on a user’s input to produce a predefined approved response.
What makes Therabot different is that it uses generative AI—a technique where a program learns from existing data to create new content in response to a prompt. Consequently, Therabot can produce novel responses based on a user’s input like other popular chatbots such as ChatGPT, allowing for a more dynamic and personalized interaction.
This isn’t the first time generative AI has been examined in a mental health setting. In 2024, researchers in Portugal conducted a study where ChatGPT was offered as an additional component of treatment for psychiatric inpatients.
The research findings showed that just three to six sessions with ChatGPT led to a significantly greater improvement in quality of life than standard therapy, medication and other supportive treatments alone.
Together, these studies suggest that both general and specialized generative AI chatbots hold real potential for use in psychiatric care. But there are some serious limitations to keep in mind. For example, the ChatGPT study involved only 12 participants—far too few to draw firm conclusions.
In the Therabot study, participants were recruited through a Meta Ads campaign, likely skewing the sample toward tech-savvy people who may already be open to using AI. This could have inflated the chatbot’s effectiveness and engagement levels.
Ethics and Exclusion
Beyond methodological concerns, there are critical safety and ethical issues to address. One of the most pressing is whether generative AI could worsen symptoms in people with severe mental illnesses, particularly psychosis.
A 2023 article warned that generative AI’s lifelike responses, combined with most people’s limited understanding of how these systems work, might feed into delusional thinking. Perhaps for this reason, both the Therabot and ChatGPT studies excluded participants with psychotic symptoms.
But excluding these people also raises questions of equity. People with severe mental illness often face cognitive challenges—such as disorganized thinking or poor attention—that might make it difficult to engage with digital tools.
Ironically, these are the people who may benefit the most from accessible, innovative interventions. If generative AI tools are only suitable for people with strong communication skills and high digital literacy, then their usefulness in clinical populations may be limited.
There’s also the possibility of AI “hallucinations”—a known flaw that occurs when a chatbot confidently makes things up—like inventing a source, quoting a nonexistent study, or giving an incorrect explanation. In the context of mental health, AI hallucinations aren’t just inconvenient, they can be dangerous.
That’s what makes these early findings both exciting and cautionary. Yes, AI chatbots might offer a low-cost way to support more people at once, but only if we fully address their limitations.
Effective implementation will require more robust research with larger and more diverse populations, greater transparency about how models are trained and constant human oversight to ensure safety. Regulators must also step in to guide the ethical use of AI in clinical settings.
With careful, patient-centered research and strong guardrails in place, generative AI could become a valuable ally in addressing the global mental health crisis—but only if we move forward responsibly.
News
Swiss laboratory uses old drugs against rare diseases
Researchers at the University of Geneva are combing through collections of approved drugs to find new therapies for rare diseases – with some success. This approach is gaining traction around the world, while pharmaceutical [...]
Nanozyme Aptasensors Show Promise for Faster Food, Health, and Environmental Testing
By pairing robust artificial enzymes with highly selective aptamers, nanozyme aptasensors could help detect disease biomarkers, pathogens, and contaminants faster, but the review shows that real-world deployment still depends on overcoming matrix interference, biofouling, [...]
Paralyzed Man Feels Sensation Again With Brain Stimulation Device
Aneuroprosthetic system has allowed a man with paralysis to grasp and lift objects and feel touch again. The device helped 42-year-old Keith Thomas of Massapequa, New York, who was paralyzed from the chest down [...]
Global Cancer Cases Could Surge 67% by 2050, New Report Warns
New data reveal major geographic disparities and highlight the urgent need for global action on prevention, early detection, and equitable access to treatment. For roughly one in five people worldwide, cancer will become part [...]
A Deadly Ebola-Like Virus Is Spreading. Are We Ready?
BU virologist Nancy Sullivan says the Bundibugyo outbreak in the Democratic Republic of the Congo underscores the need for broader outbreak preparedness. The death of a nurse marked the moment health officials recognized that [...]
Why Most Animal Viruses Never Become Human Pandemics
From receptor mismatch to risky human-animal interfaces, this article explains why spillover is common but true pandemic emergence remains rare. Introduction Humans are constantly exposed to animal viruses through farming, wildlife contact, and the [...]
Stem cell organoids repair heart microvessels in coronary artery disease models
A Stanford University team has shown that vascular organoids derived from human stem cells can repair the heart’s microvessel network in pigs with ischaemic heart disease – a proof-of-concept advancement that could open new therapeutic [...]
Goodbye GP waiting rooms, hello prevention at home
Prevention is suddenly everywhere in NHS reform. The recent £340m community pharmacy deal is moving more services onto the high street. Community Diagnostic Centres are being expanded, and the Neighbourhood Health Framework sets out [...]
Ebola control is weakened by mistrust and cultural insensitivity
Effective response depends on cooperation with communities and frontline workers, writes Zaeem ul Haq The current Bundibugyo Ebola outbreak in the Democratic Republic of the Congo (DRC) and Uganda is exposing dangerous gaps in [...]
Building the Brain Requires Millions of Dangerous DNA Breaks
Scientists discovered that building a healthy brain involves an unexpected step: young neurons routinely break and rapidly repair their own DNA. As the brain develops, newly formed nerve cells must travel through tightly packed tissue [...]
One Tiny Change May Explain How Viruses Jump From Bats to Humans
Scientists found that one tiny genetic change may determine whether a bat virus stays in bats or becomes a human threat. Most infectious disease outbreaks begin when a virus or other pathogen crosses from animals into [...]
Scientists Discover 250+ Genes That Could Lead to New Ways To Prevent Melanoma
The world’s largest study of mole genetics identified hundreds of genes tied to melanoma risk, uncovering potential new drug targets and paving the way for more accurate melanoma screening and prevention. Researchers at QIMR [...]
Breakthrough Diabetes Treatment Reprograms the Immune System
An engineered stem cell therapy reversed new-onset Type 1 diabetes in mice by shifting the immune system away from attacking insulin-producing cells. For more than a century, people with Type 1 diabetes have relied [...]
Taking the world’s temperature: WHO chief spotlights global health emergencies
Taking the world’s temperature on pressing health matters, WHO Director-General Tedros Adhanom Ghebreyesus provided the latest on current global challenges - and successes when it comes to international cooperation. “The outbreaks of hantavirus, Ebola and Marburg all show [...]
Scientists Create Tiny “Mini Livers” That Could One Day Replace Liver Transplants
Engineered tissue grafts could help perform key liver functions and benefit thousands of people living with liver failure. The liver is one of the body’s hardest-working organs, carrying out hundreds of vital jobs, from [...]
NanoMedical Brain/Cloud Interface – Explorations and Implications. A new book from Frank Boehm
New book from Frank Boehm, NanoappsMedical Inc Founder: This book explores the future hypothetical possibility that the cerebral cortex of the human brain might be seamlessly, safely, and securely connected with the Cloud via [...]















