Millions of people in England may be living with Long Covid without even realizing it.
A large-scale analysis found that nearly 10% suspect they might have the condition but remain uncertain, often due to lack of diagnosis, stigma, or self-doubt.
Many Are Unsure If They Have Long Covid
Nearly one in ten people (9.1%) in England suspect they may have Long Covid but are unsure, according to a new analysis of NHS England survey data conducted by the University of Southampton.
Researchers also found that 4.8% of respondents reported having Long Covid, with higher rates among individuals from disadvantaged backgrounds, certain ethnic groups, parents or caregivers, and those with existing long-term health conditions.
The study, published today (March 18) in the journal Health Expectations, highlights ongoing disparities in how Long Covid affects different populations.
The Unfair Burden of Long Covid
Professor Nisreen A. Alwan, a leading Long Covid researcher and co-author of the study, emphasized the disproportionate impact of the condition.
"This analysis adds further evidence of the unfairness of Long Covid, with people who are already disadvantaged in society more likely to be affected.
"It also shows us that many people aren't sure if they have it, and may need diagnosis, treatment, and support.
"Long Covid is still a very significant issue impacting individuals, families, the economy and wider society. We need to do more to prevent it, diagnose it, and properly support people who are affected by it."
A Widespread Yet Uncertain Condition
Long Covid is a chronic condition induced by COVID-19 infection that can have a significant impact on people's daily lives. Symptoms include fatigue, feeling short of breath, 'brain fog', and heart palpitations, amongst many others.
University of Southampton researchers analysed over 750,000 responses to the GP Patient Survey (England) 2023 to explore the prevalence of Long Covid, and the factors associated with both having the condition and being uncertain of having it.
Why Some People Stay Undiagnosed
They found that people aged under 25 years, males, people from particular ethnic minorities, and people without long-term conditions were more likely to be unsure if they had Long Covid.
Men are generally less likely to seek medical advice than women, which could partly explain their higher level of uncertainty. The team also says stigma and self-doubt could discourage people from seeking a diagnosis.
Raising Awareness and Bridging Gaps
Mirembe Woodrow, who is studying for a PhD at Southampton and who carried out the analysis, said: "We were really surprised to find so many people weren't sure whether they had Long Covid or not, and the study shows there is still work to do to increase awareness of the condition and remove barriers to accessing diagnosis, treatment, and support.
"We don't want Long Covid to be another factor that contributes to the widening health gap in the UK."
Long Covid Uncertainty Persists
The most recent data from the 2024 GP Patient Survey indicates Long Covid prevalence and uncertainty are not declining (5.0% and 9.0%). Professor Alwan's team intends to carry out further work using the survey to understand what could be driving inequality in prevalence, impact, and support for Long Covid.
Reference: "Exploring Long Covid prevalence and patient uncertainty by sociodemographic characteristics using GP Patient Survey data" 17 March 2025, Health Expectations.
DOI: 10.1111/hex.70202
News
Plant Discovery Could Transform How Medicines Are Made
Scientists have uncovered an unexpected way plants make powerful chemicals, revealing hidden biological connections that could transform how medicines are discovered and produced. Plants produce protective chemicals called alkaloids as part of their natural [...]
Scientists Develop IV Therapy That Repairs the Brain After Stroke
New nanomaterial passes the blood-brain barrier to reduce damaging inflammation after the most common form of stroke. When someone experiences a stroke, doctors must quickly restore blood flow to the brain to prevent death. [...]
Analyzing Darwin’s specimens without opening 200-year-old jars
Scientists have successfully analyzed Charles Darwin's original specimens from his HMS Beagle voyage (1831 to 1836) to the Galapagos Islands. Remarkably, the specimens have been analyzed without opening their 200-year-old preservation jars. Examining 46 [...]
Scientists discover natural ‘brake’ that could stop harmful inflammation
Researchers at University College London (UCL) have uncovered a key mechanism that helps the body switch off inflammation—a breakthrough that could lead to new treatments for chronic diseases affecting millions worldwide. Inflammation is the [...]
A Forgotten Molecule Could Revive Failing Antifungal Drugs and Save Millions of Lives
Scientists have uncovered a way to make existing antifungal drugs work again against deadly, drug-resistant fungi. Fungal infections claim millions of lives worldwide each year, and current medical treatments are failing to keep pace. [...]
Scientists Trap Thyme’s Healing Power in Tiny Capsules
A new micro-encapsulation breakthrough could turn thyme’s powerful health benefits into safer, smarter nanodoses. Thyme extract is often praised for its wide range of health benefits, giving it a reputation as a natural medicinal [...]
Scientists Develop Spray-On Powder That Instantly Seals Life-Threatening Wounds
KAIST scientists have created a fast-acting, stable powder hemostat that stops bleeding in one second and could significantly improve survival in combat and emergency medicine. Severe blood loss remains the primary cause of death from [...]
Oceans Are Struggling To Absorb Carbon As Microplastics Flood Their Waters
New research points to an unexpected way plastic pollution may be influencing Earth’s climate system. A recent study suggests that microscopic plastic pollution is reducing the ocean’s capacity to take in carbon dioxide, a [...]
Molecular Manufacturing: The Future of Nanomedicine – New book from Frank Boehm
This book explores the revolutionary potential of atomically precise manufacturing technologies to transform global healthcare, as well as practically every other sector across society. This forward-thinking volume examines how envisaged Factory@Home systems might enable the cost-effective [...]
New Book! NanoMedical Brain/Cloud Interface – Explorations and Implications
New book from Frank Boehm, NanoappsMedical Inc Founder: This book explores the future hypothetical possibility that the cerebral cortex of the human brain might be seamlessly, safely, and securely connected with the Cloud via [...]
Global Health Care Equivalency in the Age of Nanotechnology, Nanomedicine and Artificial Intelligence
A new book by Frank Boehm, NanoappsMedical Inc. Founder. This groundbreaking volume explores the vision of a Global Health Care Equivalency (GHCE) system powered by artificial intelligence and quantum computing technologies, operating on secure [...]
Miller School Researchers Pioneer Nanovanilloid-Based Brain Cooling for Traumatic Injury
A multidisciplinary team at the University of Miami Miller School of Medicine has developed a breakthrough nanodrug platform that may prove beneficial for rapid, targeted therapeutic hypothermia after traumatic brain injury (TBI). Their work, published in ACS [...]
COVID-19 still claims more than 100,000 US lives each year
Centers for Disease Control and Prevention researchers report national estimates of 43.6 million COVID-19-associated illnesses and 101,300 deaths in the US during October 2022 to September 2023, plus 33.0 million illnesses and 100,800 deaths [...]
Nanomedicine in 2026: Experts Predict the Year Ahead
Progress in nanomedicine is almost as fast as the science is small. Over the last year, we've seen an abundance of headlines covering medical R&D at the nanoscale: polymer-coated nanoparticles targeting ovarian cancer, Albumin recruiting nanoparticles for [...]
Lipid nanoparticles could unlock access for millions of autoimmune patients
Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted lipid nanoparticles (tLNPs) is designed to deliver [...]
The Brain’s Strange Way of Computing Could Explain Consciousness
Consciousness may emerge not from code, but from the way living brains physically compute. Discussions about consciousness often stall between two deeply rooted viewpoints. One is computational functionalism, which holds that cognition can be [...]















