Written by AZoNano:
Cornell dots or C dots are nanoparticles that are emerging as promising therapeutic tools to detect and treat cancer.
These nanoparticles were developed by Ulrich Wiesner, the Spencer T. Olin Professor of Engineering at Cornell University over 12 years ago. These ultrasmall particles have now proved that they are capable of killing cancer cells without linking a cytotoxic drug.
Michelle Bradbury, director of intraoperative imaging at Memorial Sloan Kettering Cancer Center and associate professor of radiology at Weill Cornell Medicine, and Michael Overholtzer, cell biologist at MSKCC headed the research endeavor, and collaborated with Wiesner. The study explains how a certain type of cell death known as ferroptosis is caused by C dots when the nanoparticles are administered in heavy doses, and the tumors experience nutrient deprivation.