From Nanowerk News:
A new ultra-high resolution “nanoscope” is capable of taking 3-D images of an entire cell and its cellular constituents in unprecedented detail, an advance that could reveal biological phenomena never before seen and bring new medical insights.The work (Cell, “Ultra-High Resolution 3D Imaging of Whole Cells”) was carried out by researchers at Yale University, Purdue University, the University of Cambridge, the Jackson Laboratory, Howard Hughes Medical Institute and the University of Oxford.
The technology incorporates several innovations in fluorescence microscopy and super-resolution microscopy and harnesses the same kind of “adaptive optics” technology used in astronomy – deformable mirrors that change shape to compensate for light distortion. In astronomy the deformable mirrors are used to compensate for atmospheric distortion to yield clear images of celestial objects. Deformable mirrors also can be used to counteract the distortion caused when light passes through biological tissue.
Image Credit: Courtesy of Huang et al./Cell
Recent News
NIH Scientists Discover Gene Responsible for Rare Eye Disease
Findings supported by the NIH pave the way for the development of genetic testing, clinical trials, and therapies. Researchers at the National Institutes of Health (NIH) and their collaborators have discovered [...]
Alzheimer’s Breakthrough: Synthetic THC Pill Proves Effective in Clinical Trial
Patients tolerated synthetic THC (dronabinol) well, without the adverse effects commonly associated with existing Alzheimer’s agitation medications. A study conducted by researchers from Johns Hopkins University School of Medicine and Tufts University School of [...]
The Future of Rare Disease Treatment with Precision Medicine
Understanding rare diseases Rare diseases affect less than 5 people out of 10,000. However, this still amounts to about 7% of the world’s population, with over 10,000 such conditions. [...]
Doctors issue warning for upcoming ‘tripledemic
The term ‘tripledemic’ has hit headlines this week as the NHS begins its Covid and fluvaccine roll-out for vulnerable adults. As the cold weather sets in, many of us have experienced a decline [...]
The FDA approved a gel that can stop bleeding from wounds in seconds
Aug 15 (Reuters) - The U.S. Food and Drug Administration has cleared Cresilon's gel to quickly control bleeding, the privately held company said on Thursday, potentially giving emergency medical [...]
High levels of microplastics found in prostate tumors, possibly linked to take-out food
The presence of microplastics in prostate tumors points to potential health risks, and researchers are calling for urgent studies to explore how take-out food may be driving this exposure. [...]
AI outperforms radiologists in brain tumor diagnosis
As artificial intelligence advances, its uses and capabilities in real-world applications continue to reach new heights that may even surpass human expertise. In the field of radiology, where a correct [...]
Breakthrough Study Reveals Molecular Clues to Dementia Origins
Work could lead to the discovery of new therapeutic targets. For the first time, researchers have identified “molecular markers” linked to degeneration—detectable changes in cells and their gene-regulating networks—that [...]
Better than blood tests? Nanoparticle potential found for assessing kidneys
In a study published July 29 in Advanced Materials, University of Texas at Dallas researchers found that X-rays of the kidneys using gold nanoparticles as a contrast agent might be [...]
Greener nanomaterials could transform how our everyday stuff is made
Tiny nanoparticles are at the forefront of materials science—with special properties that make them great at absorbing light in solar panels, cleaning wastewater, and delivering drugs precisely. Some nanoparticles take the form of sheets [...]
AI could predict breast cancer risk via ‘zombie cells’
Women worldwide could see better treatment with new AI technology, which enables better detection of damaged cells and more precisely predicts the risk of getting breast cancer, [...]
Through the eyes of a cat – biomimicry of feline eyes may revolutionize robotic vision
In a recent study published in the journal Science Advances, researchers leveraged crucial aspects of feline eyes, particularly their tapetum lucidum and vertically elongated pupils (VP), to develop a monocular [...]
New Alzheimer’s Therapy Shows Remarkable Results in Animal Trials
A study from TUM demonstrates a promising therapeutic approach. Researchers at the Technical University of Munich (TUM) have made promising advances in preventing Alzheimer’s by developing a new therapeutic strategy. Their approach focuses [...]
Rewriting Cancer’s Blueprint: New Study Challenges Old Theories
A new study argues for a revised clonal evolution model of cancer, incorporating genetic and non-genetic factors to improve understanding and treatment. Like all living organisms, cancer cells are [...]
Microplastics Everywhere: Experts Demand Worldwide Treaty Before It’s Too Late
A new report calls for global action on plastic pollution, urging reductions in plastic production and microplastic emissions. Researchers stress the importance of addressing plastic pollution through both scientific [...]
Blood tests could soon predict your risk of Alzheimer’s
Scientists are closing in on biomarkers that reflect the progression of Alzheimer’s disease and could improve treatments. Like many Alzheimer’s researchers, neurologist Randall Bateman is not prone to effusiveness, [...]
Recharging mitochondria—nanoflowers offer a new way to simulate energy production
When we need to recharge, we might take a vacation or relax at the spa. But what if we could recharge at the cellular level, fighting against aging and [...]
Revealing the Invisible: Living Cells Can Be Seen With Infrared Light
IST’s new infrared microscopy technique allows for the detailed imaging of biomolecules in cells, supporting advancements in biotechnology and cellular therapies. In an effort to advance biotechnology innovations, scientists [...]
3,600+ Chemicals From Food Packaging Found in Human Bodies
A recent review has uncovered the widespread presence of food contact chemicals (FCC) in humans, identifying 3,601 chemicals used in food packaging and related products found in the human [...]
CREME: A New AI-Powered Virtual Lab to Help Cure Genetic Diseases
CREME, an AI-powered virtual lab, developed at Cold Spring Harbor Laboratory, offers a revolutionary approach to genetic research by simulating CRISPR interference (CRISPRi). This tool enables scientists to perform [...]
New Research Reveals That Cannabis Can Reverse Brain Aging
Researchers in Bonn examine how treatment with tetrahydrocannabinol affects the mTOR metabolic pathway. A low-dose, long-term administration of cannabis has been shown to not only reverse aging processes in the brain [...]
Cardiovascular risks of COVID-19 antivirals
Several antivirals, including remdesivir, Paxlovid, molnupiravir, and monoclonal antibodies like tixagevimab and cilgavimab, have been repurposed to treat the coronavirus disease 2019 (COVID-19) or received emergency use authorization (EUA). [...]
Your eyes could reveal the first signs of many diseases
Melissa, a 30-year-old educator, came to the emergency department with a sudden onset of double vision. She had not been in an accident or suffered any trauma and had [...]
New insight into the causes of autoimmune diseases
Autoimmune diseases are widespread and notoriously difficult to treat. In part, this is because why the immune system attacks its own tissues in patients with these conditions remains poorly [...]
COVID-19 reduces male fertility by affecting semen quality and hormone levels
In a recent study published in the journal PLOS ONE, researchers conducted a systematic review and meta-analyzed data on the impact of coronavirus disease 2019 (COVID-19) on male reproductive hormones [...]
New Alzheimer’s Study Unlocks the Secrets of Aging Brain Cells
New method uses patient-derived neurons to effectively simulate late-onset Alzheimer’s and identify possible treatments. Researchers at Washington University School of Medicine in St. Louis have created a technique to explore the impact of [...]
Lockdowns prematurely aged teenagers’ brains, study suggests
Teenage girls' brains may have prematurely aged by up to four years during the Covid pandemic, an American study suggests. Adolescent boys weren't immune either with their brain's also [...]
Long COVID Still a Mystery: Routine Labs Show No Reliable Biomarkers
Routine lab tests are not reliable for diagnosing Long COVID, according to a new study. The research found that no clinical lab values could serve as biomarkers, highlighting the [...]
Tiny magnetic robots could treat bleeds in the brain
Researchers have created nanoscale robots which could be used to manage bleeds in the brain caused by aneurysms. The development could enable precise, relatively low-risk treatment of brain aneurysms, which [...]
Turning Mosquito Spit Into a Weapon Against the West Nile Virus and Other Deadly Diseases
Anita Saraf investigates mosquito saliva to understand how viruses like dengue and West Nile are transmitted, using mass spectrometry to identify potential targets for vaccines and treatments. You might [...]
Ethics in Nanomedicine: Key Issues and Principles
Nanomedicine, a branch of nanotechnology, is revolutionizing healthcare by enabling the manipulation of materials at the nanoscale to diagnose, treat, and prevent diseases. Unlike traditional treatments, nanoparticles (NPs) are [...]
A call for robust H5N1 influenza preparedness and response
As the global threat of H5N1 influenza looms with outbreaks across species and continents including the U.S., three international vaccine and public health experts say it is time to [...]
Mucosal COVID-19 boosters outperform mRNA shots in preventing upper airway infections
In a recent study published in Nature Immunology, a team of researchers from the United States used non-human primate models to compare the protection conferred by an intramuscular booster dose [...]
How Space Travel Really Changes Astronauts – From the Inside Out
International team reveals previously unknown effects on physiology that could shape the future of long-duration space missions. Researchers have discovered significant changes in the gut microbiome due to spaceflight, [...]
Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure
Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized [...]
Scientists Develop Game-Changing Needle-Free COVID-19 Intranasal Vaccine
A new mucosal COVID-19 vaccine poised to revolutionize the delivery process is especially beneficial for those with a fear of needles. A next-generation COVID-19 mucosal vaccine is set to be a [...]
Scientists Develop All-in-One Solution To Catch and Destroy “Forever Chemicals”
A new water treatment system developed by UBC researchers efficiently removes and destroys PFAS pollutants using a dual-action catalyst, offering a sustainable and cost-effective solution for water purification challenges. [...]
New method accelerates drug discovery from years to months
Researchers from the University of Cincinnati College of Medicine and Cincinnati Children's Hospital have found a new method to increase both speed and success rates in drug discovery. The [...]
A new smart mask analyzes your breath to monitor your health
Your breath can give away a lot about you. Each exhalation contains all sorts of compounds, including possible biomarkers for disease or lung conditions, that could give doctors a [...]
Study reveals the role of blood clotting in COVID-19
In a study that reshapes what we know about COVID-19 and its most perplexing symptoms, scientists have discovered that the blood coagulation protein fibrin causes the unusual clotting and [...]
A Novel Cancer Vaccine Combining Nano-11 and ADU-S100
In a recent article published in npj Vaccines, researchers detailed the development of a novel cancer vaccine that combines a plant-derived nanoparticle adjuvant, Nano-11, with a clinically tested STING agonist, [...]
AI spots cancer and viral infections with nanoscale precision
Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells. The findings, [...]
Tiny shards of plastic are increasingly infiltrating our brains, study says
Human brain samples collected at autopsy in early 2024 contained more tiny shards of plastic than samples collected eight years prior, according to a preprint posted online in May. A preprint is a [...]
Scientists Have Discovered Strange DNA in Our Brains – and It Could Be Shortening Our Lives
According to the research, these mitochondrial DNA insertions could be linked to early death. Mitochondria in brain cells frequently insert their DNA into the nucleus, potentially impacting lifespan, as those with [...]
Watch Out After a Hospital Stay: You Could Be Exposing Your Family to Superbugs
Research indicates hospitals contribute to the local spread of antibiotic-resistant infections. A recent study published in the journal Infection Control & Hospital Epidemiology by the Society for Healthcare Epidemiology of America [...]
Molecular Trickery: How COVID-19 Silently Sabotages the Human Immune System
Researchers have discovered that SARS-CoV-2 manipulates the human immune system by forcing cells to produce non-functional proteins, hindering the body’s antiviral defenses. This groundbreaking study by teams from prestigious Brazilian universities [...]
How is AI Transforming Drug Discovery?
Artificial intelligence (AI) is currently at the forefront of everyone’s minds, with its exciting potential to revolutionize every industry and alter traditional workflow. The growing impact of AI [...]
Unique Plant Species Provide Surprising New Insights Into Cancer
New research explores the adaptation strategies of polyploid plants, offering insights for cancer treatment and enhancing crop resilience against environmental challenges. Whole genome duplication (WGD) occurs across all kingdoms [...]
98% Efficiency: Scientists Unveil Game-Changing Nanoplastic Removal Technology
A team at the University of Missouri has devised a method to eliminate most nanoplastics from water using eco-friendly solvents, suitable for both fresh and saltwater applications. Nanoplasticst are [...]
New insights into COVID-19 spike protein offer hope for universal vaccines
A team led by Jose Onuchic at Rice University and Paul Whitford at Northeastern University, both researchers at the National Science Foundation Physics Frontiers Center at the Center for [...]
Leave A Comment