NanoApps Medical is investigating the possibility that superparamagnetic nanoparticles (SPIONs) (Figure 1) and other classes of nanoparticles (e.g., gold coated nanoshells) (Figure 2) might have the capacity to target cancerous tumors, metastasizing cancer cells, pathogens, etc. to deactivate/eliminate them via hypothermia.

This means that once the nanoparticles are adhered to their targets, they would be heated by an external source (a magnetic field in the case of SPIONs, and near-infrared laser light in the case of gold nanoshells) to inflict irreversible thermal damage to these entities through the catastrophic disruption of their cell membranes.

Additionally, gold nanoshells may be synthesized to be hollow, which means that they might be loaded with powerful drugs to impart a dual activity against their targets. A further advantage of this strategy is that the “collateral damage” to surrounding healthy cells will be minimized as the thermal “blast zones” and drug delivery would be highly localized, in stark contrast to conventional chemotherapies that flood the patient with toxic chemicals.

Read more at nanoappsmedical.com

Image Credit:     Alias Studio Sydney

News This Week

A ‘cancer lab’ on chip

Finding out you have cancer is bad enough, but to then have to go to hospital for a painful and invasive biopsy to try to identify the exact type of tumor can be deeply [...]

Nanoparticles Heal Spinal Cord Injuries

The zealous immune response to injuries is known to cause paralyzing damage in spinal cord injury (SCI). Engineers have now created unique nanoparticles that redirect immune cells away from the spinal cord, promoting regeneration [...]