The Omicron BA.5 subvariant is no longer the dominant cause of Covid-19 infections in the United States, according to estimates released Friday by the US Centers for Disease Control and Prevention.
Instead, a host of new sublineages – offshoots of BA.2, BA.4 and BA.5 – are now responsible for the majority of new infections in this country. Dr. Peter Hotez, director of the Center for Vaccine Development at Texas Children’s Hospital, calls these many new lineages “Scrabble variants” because they contain letters like X and Q that get high scores in the game.
The new variants descend from slightly different branches of the Omicron family tree, but they have evolved to share some of the same changes in their genomes that help them slip past our immunity against the virus.
The gaggle of new variants have been gaining ground against BA.5, which has dominated Covid-19 infections in the United States since July. BA.5 now accounts for 49.6% of new infections in this country.
Two variants, BQ.1 and BQ.1.1, have been growing especially fast. At the beginning of October, each one accounted for about 1% of new infections in the United States, but they have been roughly doubling in prevalence each week. Together, they now account for more than 1 in 4 new Covid-19 infections nationwide, according to CDC data.
BQ.1 is causing about 14% of new infections; BQ.1.1. is causing 13% of new infections. BA.4.6 is causing another 10%. BF.7 accounts for 7.5% of newly diagnosed Covid-19. A slew of other new variants accounts for smaller pieces of the Covid-19 pie.
These variants are not evenly distributed across the US. BQ.1.1 is now causing about 1 in 5 new Covid-19 infections in the Northeast, where cases and hospitalizations are rising. But that strain is causing just 3% of new Covid-19 infections in the Pacific Northwest.
These variants are slightly different from each other, but they all carry some of the same key mutations that help them skirt immunity from vaccines and past infections. This makes them more likely to lead to breakthrough infections and reinfections.
In a statement released Friday, the World Health Organization’s Technical Advisory Group on SARS-CoV-2 Virus Evolution said the most mutated families of the rising subvariants – XBB and BQ.1 – aren’t different enough from Omicron to be considered separate variants of concern.
XBB was detected in the United States in September, but it is not causing a significant number of cases in this country. It is particularly widespread in Singapore, where it is now the dominant circulating strain.
“The two sublineages remain part of Omicron, which continues to be a variant of concern,” the group said in a statement.
Image Credit: Envato Elements

News
Does Space-Time Really Exist?
Is time something that flows — or just an illusion? Exploring space-time as either a fixed “block universe” or a dynamic fabric reveals deeper mysteries about existence, change, and the very nature of reality. [...]
Unlocking hidden soil microbes for new antibiotics
Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil [...]
By working together, cells can extend their senses beyond their direct environment
The story of the princess and the pea evokes an image of a highly sensitive young royal woman so refined, she can sense a pea under a stack of mattresses. When it comes to [...]
Overworked Brain Cells May Hold the Key to Parkinson’s
Scientists at Gladstone Institutes uncovered a surprising reason why dopamine-producing neurons, crucial for smooth body movements, die in Parkinson’s disease. In mice, when these neurons were kept overactive for weeks, they began to falter, [...]
Old tires find new life: Rubber particles strengthen superhydrophobic coatings against corrosion
Development of highly robust superhydrophobic anti-corrosion coating using recycled tire rubber particles. Superhydrophobic materials offer a strategy for developing marine anti-corrosion materials due to their low solid-liquid contact area and low surface energy. However, [...]
This implant could soon allow you to read minds
Mind reading: Long a science fiction fantasy, today an increasingly concrete scientific goal. Researchers at Stanford University have succeeded in decoding internal language in real time thanks to a brain implant and artificial intelligence. [...]
A New Weapon Against Cancer: Cold Plasma Destroys Hidden Tumor Cells
Cold plasma penetrates deep into tumors and attacks cancer cells. Short-lived molecules were identified as key drivers. Scientists at the Leibniz Institute for Plasma Science and Technology (INP), working with colleagues from Greifswald University Hospital and [...]
This Common Sleep Aid May Also Protect Your Brain From Alzheimer’s
Lemborexant and similar sleep medications show potential for treating tau-related disorders, including Alzheimer’s disease. New research from Washington University School of Medicine in St. Louis shows that a commonly used sleep medication can restore normal sleep patterns and [...]
Sugar-Coated Nanoparticles Boost Cancer Drug Efficacy
A team of researchers at the University of Mississippi has discovered that coating cancer treatment carrying nanoparticles in a sugar-like material increases their treatment efficacy. They reported their findings in Advanced Healthcare Materials. Over a tenth of breast [...]
Nanoparticle-Based Vaccine Shows Promise in Fighting Cancer
In a study published in OncoImmunology, researchers from the German Cancer Research Center and Heidelberg University have created a therapeutic vaccine that mobilizes the immune system to target cancer cells. The researchers demonstrated that virus peptides combined [...]
Quantitative imaging method reveals how cells rapidly sort and transport lipids
Lipids are difficult to detect with light microscopy. Using a new chemical labeling strategy, a Dresden-based team led by André Nadler at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) and [...]
Ancient DNA reveals cause of world’s first recorded pandemic
Scientists have confirmed that the Justinian Plague, the world’s first recorded pandemic, was caused by Yersinia pestis, the same bacterium behind the Black Death. Dating back some 1,500 years and long described in historical texts but [...]
“AI Is Not Intelligent at All” – Expert Warns of Worldwide Threat to Human Dignity
Opaque AI systems risk undermining human rights and dignity. Global cooperation is needed to ensure protection. The rise of artificial intelligence (AI) has changed how people interact, but it also poses a global risk to human [...]
Nanomotors: Where Are They Now?
First introduced in 2004, nanomotors have steadily advanced from a scientific curiosity to a practical technology with wide-ranging applications. This article explores the key developments, recent innovations, and major uses of nanomotors today. A [...]
Study Finds 95% of Tested Beers Contain Toxic “Forever Chemicals”
Researchers found PFAS in 95% of tested beers, with the highest levels linked to contaminated local water sources. Per- and polyfluoroalkyl substances (PFAS), better known as forever chemicals, are gaining notoriety for their ability [...]
Long COVID Symptoms Are Closer To A Stroke Or Parkinson’s Disease Than Fatigue
When most people get sick with COVID-19 today, they think of it as a brief illness, similar to a cold. However, for a large number of people, the illness doesn't end there. The World [...]