U.S. Centers for Disease Control and Prevention Director Rochelle Walensky has experienced a COVID rebound after a course of Paxlovid, the federal health agency announced Monday morning.
She is isolating at home and will participate in meetings virtually, the agency added.
Walensky joins a short list of prominent U.S. pandemic figures, including President Joe Biden and presidential physician Dr. Anthony Fauci, who’ve tested negative, then positive again after taking the popular drug, prescribed for those with documented COVID who are at high risk for severe disease.
Just how rare are rebounds?
Paxlovid, approved for use by the U.S. Food and Drug Administration under an emergency use authorization, has become known for its “rebound cases,” referred to by the CDC as a “brief return of symptoms.”
Such rebounds, however, can happen with or without Paxlovid, Andy Pekosz, virologist at the Johns Hopkins Bloomberg School of Public Health, recently told Fortune.
While the U.S. Centers for Disease Control and Prevention says that COVID rebounds are rare, they could be more common than we know, as most individuals with COVID stop testing after they receive a negative result, he added.
“After I finished the five days of Paxlovid, I reverted to negative on an antigen test for three days in a row,” Fauci, 81, said during an event at Foreign Policy’s Global Health Forum, Bloomberg reported. “And then on the fourth day, just to be absolutely certain, I tested myself again.”
“I reverted back to positive.”
Fauci began a second course of Paxlovid when symptoms emerged “much worse than the first go-around,” he said. In May the CDC issued a health advisory about such rebounds, saying there was no evidence that additional treatment is needed for rebound cases.
In June, Pfizer, which manufactures Paxlovid, announced that it would stop adding new participants to a trial of the drug among COVID patients at low risk of hospitalization and death. The study failed to demonstrate that the drug reduced symptoms, or hospitalizations and deaths, in a statistically significant way, according to Bloomberg.
But Paxlovid may be undeservedly gaining a bad rap, Pekosz cautioned.
“I’ll still point to the fact that it’s working in terms of keeping people out of the hospital—that’s the most important thing right now,” he said, adding that it may need to be retooled to better address Omicron subvariants.
Image Credit: Pfizer
News
Bowel and Ovarian Cancers Are Dramatically Rising in Young Adults, Scientists Aren’t Sure Why
Cancer incidence is increasing, especially among younger adults, and current risk factors don’t fully account for the trend. Scientists suggest other underlying causes may be contributing. Cancer patterns in England are shifting in a [...]
New Immune Pathway Could Supercharge mRNA Cancer Vaccines
A surprising backup system in the immune response to mRNA vaccines may hold the key to more effective cancer treatments. The arrival of mRNA vaccines against SARS-CoV-2 in 2020 marked a turning point in the COVID-19 pandemic. Today, [...]
Scientists Discover “Molecular Switch” That Fuels Alzheimer’s Brain Inflammation
A newly identified trigger of brain inflammation could offer a fresh target for slowing Alzheimer’s progression. The brain has its own built-in immune system that identifies threats and responds to them. In Alzheimer’s disease, growing evidence [...]
Molecular Manufacturing: The Future of Nanomedicine – New book from NanoappsMedical Inc.
This book explores the revolutionary potential of atomically precise manufacturing technologies to transform global healthcare, as well as practically every other sector across society. This forward-thinking volume examines how envisaged Factory@Home systems might enable the cost-effective [...]
Forgotten Medicinal Plant Shows Promise in Fighting Dangerous Superbugs
A traditional medicinal plant, tormentil, shows promise against antibiotic-resistant bacteria in laboratory tests. Its compounds work by limiting bacterial growth and boosting antibiotic performance. Before the development of modern antibiotics, plant-based remedies were commonly [...]
NanoMedical Brain/Cloud Interface – Explorations and Implications. A new book from Frank Boehm
New book from Frank Boehm, NanoappsMedical Inc Founder: This book explores the future hypothetical possibility that the cerebral cortex of the human brain might be seamlessly, safely, and securely connected with the Cloud via [...]
New Research Finds Shocking Link Between Chili Peppers and Cancer
If you love spicy food, you are not alone. But scientists are taking a closer look at whether eating a lot of chili peppers could affect your cancer risk. Could your love of spicy [...]
New book from Nanoappsmedical Inc. – Global Health Care Equivalency
A new book by Frank Boehm, NanoappsMedical Inc. Founder. This groundbreaking volume explores the vision of a Global Health Care Equivalency (GHCE) system powered by artificial intelligence and quantum computing technologies, operating on secure [...]
Scientists Create “Neurobots” – Living Machines With Their Own Nervous Systems
Neurobots—xenobots with neurons—show self-organized nervous systems and enhanced behaviors, revealing new insights into how biology builds functional structures. In 2020, researchers at Tufts University developed tiny living structures known as xenobots using frog cells. These microscopic organisms [...]
Our books now available worldwide!
Online Sellers other than Amazon, Routledge, and IOPP Indigo Global Health Care Equivalency in the Age of Nanotechnology, Nanomedicine and Artifcial Intelligence Global Health Care Equivalency In The Age Of Nanotechnology, Nanomedicine And Artificial [...]
Amazonian Chocolate Could Become the Next Superfood, Scientists Say
New research into Amazonian cocoa reveals that its value may extend beyond flavor alone. Chocolate from the Amazon is already known worldwide for its distinctive taste, but new research suggests it may offer even [...]
Nanobody repairs misfolded CFTR inside cells, boosting function in cystic fibrosis
A tiny antibody component could fundamentally transform the treatment of cystic fibrosis: For the first time, researchers have succeeded in developing a so-called nanobody that penetrates directly into human cells and can repair the [...]
20-Year Study Finds Daily Multivitamins Don’t Extend Lifespan
A large, decades-long study of over 390,000 U.S. adults challenges a widespread assumption about daily multivitamins. Multivitamins are a daily habit for millions of Americans, often taken with the expectation that they will extend [...]
Novel Investment Paradigms for Regenerative Healthcare Ecosystems
Introduction The transition toward regenerative healthcare ecosystems—anchored in wellness optimization, disease prevention, eradication strategies, and healthy longevity—necessitates a structural reconfiguration of capital architectures, governance models, and incentive design. Regenerative healthcare, by definition, transcends episodic [...]
What If Consciousness Exists Beyond Your Brain
Scientists still don’t know how consciousness emerges from the brain. New ideas suggest it may not emerge at all, but instead be a basic feature of reality. Is consciousness produced by the brain, or [...]
Scientists Discover Way To Treat Lung Cancer and Its Deadly Side Effect Together
A new approach using lipid nanoparticles to deliver genetic material is showing promise in tackling two major challenges in lung cancer at once.Researchers at Oregon State University have designed a new way to tackle two of [...]
