DNA Script has raised $38.5 million in new financing to commercialize a process that it claims is the first big leap forward in manufacturing genetic material.

The revolution in synthetic biology that’s reshaping industries from medicine to agriculture rests on three, equally important pillars.

They include: analytics — the ability to map the genome and understand the function of different genes; synthesis — the ability to manufacture DNA to achieve certain functions; and gene editing — the CRISPR-based technologies that allow for the addition or subtraction of genetic code.

New technologies have already been introduced to transform the analytics and editing of genomes, but little progress has been made over the past 50 years in the ways in which genetic material is manufactured. That’s exactly the problem that DNA Script is trying to solve.

Traditionally, making DNA involved the use of chemical compounds to synthesize (or write) DNA in chains that were limited to around 200 nucleotide bases. Those synthetic pieces of genetic code are then assembled to make a gene.

DNA Script’s technology holds the promise of making longer chains of nucleotides by mirroring the enzymatic process through which DNA is assembled within cells — with fewer errors and no chemical waste material. The enzymatic process can accelerate commercial applications in healthcare, chemical manufacturing and agriculture.

“Any technology that can make that faster is going to be very valuable,” says Christopher Voigt, a synthetic biologist at the Massachusetts Institute of Technology in Cambridge, told the journal Nature.

DNA Script isn’t the only company in the market that’s looking to make the leap forward in enzymatic DNA production. Nuclear, a startup working with Harvard University’s famed geneticist, George Church, and Ansa Bio, a startup affiliated with Jay Keasling’s Berkeley lab at the University of California, are also moving forward with the technology.

But the Paris-based company has achieved some milestones that would make its technology potentially the first to come to market with a commercially viable approach.

Image Credit:  Envato

Read more at techcrunch.com

News This Week

Green Method to Make Nanoparticles and Ultrafine Powder

A novel freeze-dissolving approach has been devised that offers greater efficiency and sustainability compared to the classic freeze-drying process to make superfine powder or nanoparticles.​​​​​​​ In the research published in the journal ACS Sustainable Chemistry & Engineering, sphere-shaped [...]

Could gold nanoparticles help treat cancer?

Gold nanoparticles are minuscule particles made of gold. From drug and gene delivery to photothermal and photodynamic therapies to screening and diagnostic tests to radiation therapy, X-ray imaging and CT scans, these small particles [...]