An international team led by scientists at the University of Sydney has demonstrated nanowire networks can exhibit both short- and long-term memory like the human brain.
“In this research we found higher-order cognitive function, which we normally associate with the human brain, can be emulated in non-biological hardware,” Dr. Loeffler said.
“This work builds on our previous research in which we showed how nanotechnology could be used to build a brain-inspired electrical device with neural network-like circuitry and synapse-like signaling.
“Our current work paves the way towards replicating brain-like learning and memory in non-biological hardware systems and suggests that the underlying nature of brain-like intelligence may be physical.”
Nanowire networks are a type of nanotechnology typically made from tiny, highly conductive silver wires that are invisible to the naked eye, covered in a plastic material, which are scattered across each other like a mesh. The wires mimic aspects of the networked physical structure of a human brain.

Advances in nanowire networks could herald many real-world applications, such as improving robotics or sensor devices that need to make quick decisions in unpredictable environments.
“This nanowire network is like a synthetic neural network because the nanowires act like neurons, and the places where they connect with each other are analogous to synapses,” senior author Professor Zdenka Kuncic, from the School of Physics, said.
“Instead of implementing some kind of machine learning task, in this study Dr. Loeffler has actually taken it one step further and tried to demonstrate that nanowire networks exhibit some kind of cognitive function.”
To test the capabilities of the nanowire network, the researchers gave it a test similar to a common memory task used in human psychology experiments, called the N-Back task.
For a person, the N-Back task might involve remembering a specific picture of a cat from a series of feline images presented in a sequence. An N-Back score of 7, the average for people, indicates the person can recognize the same image that appeared seven steps back.
“What we did here is manipulate the voltages of the end electrodes to force the pathways to change, rather than letting the network just do its own thing. We forced the pathways to go where we wanted them to go,” Dr. Loeffler said.
“When we implement that, its memory had much higher accuracy and didn’t really decrease over time, suggesting that we’ve found a way to strengthen the pathways to push them towards where we want them, and then the network remembers it.
“Neuroscientists think this is how the brain works, certain synaptic connections strengthen while others weaken, and that’s thought to be how we preferentially remember some things, how we learn and so on.”
The researchers said when the nanowire network is constantly reinforced, it reaches a point where that reinforcement is no longer needed because the information is consolidated into memory.
“It’s kind of like the difference between long-term memory and short-term memory in our brains,” Professor Kuncic said.
“If we want to remember something for a long period of time, we really need to keep training our brains to consolidate that, otherwise it just kind of fades away over time.
“One task showed that the nanowire network can store up to seven items in memory at substantially higher than chance levels without reinforcement training and near-perfect accuracy with reinforcement training.”
News
FDA approves breakthrough drug to treat advanced pancreatic cancer
The Food and Drug Administration (FDA) approved on Wednesday a drug that could extend the survival of those with metastatic pancreatic cancer. The drug, called daraxonrasib, will be sold under the brand name Rasonque [...]
AI Decodes a Hidden DNA Signal Linked to Disease-Causing Mutations
Machine learning identifies the likely “initiator” and enables new predictions about DNA mutations that can cause disease. Every human cell depends on tens of thousands of genes being switched on at the right time [...]
Pope Leo Urges Global Response to Congo’s Deadliest Ebola Outbreak
Pope Leo called for international action to address the Ebola outbreak in the Democratic Republic of Congo. The epidemic has claimed over 2,500 lives and is the nation's largest recorded outbreak. The Pope emphasized [...]
Is there a summer COVID-19 surge this year? Yep, it’s ramping up again
Hantavirus. Ebola. West Nile. Measles. And, of course, cyclospora — that stomach parasite making people miserable across the country. Americans have plenty to worry about this summer. But remember COVID-19? It may not be [...]
Natural Compound in Broccoli Could Help Treat a Rare, Incurable Neurological Disease
Swinburne researchers have discovered how broccoli could help treat an extremely rare and incurable disease that affects only about 200 Australians. A naturally occurring compound in broccoli is being investigated as a possible treatment [...]
Antibody recycling, FcRn and the next generation of biologics
FcRn plays a central role in regulating the half-life of IgG antibodies and albumin, making it a critical target in both antibody engineering and autoimmune disease therapy. This article explores the biology of FcRn, [...]
Ebola kills 2,300 in three months with no vaccine available for Congo’s deadliest ever outbreak
It’s Congo’s 17th outbreak, with a toll that has eclipsed that of the country’s 2018-2020 outbreak when 2,299 deaths out of 3,481 cases were recorded. The latest data shows 101 new cases and 33 [...]
Beyond an Agency: How AI, Creativity and Commercialization Are Converging Into a New Growth Model
At a moment when AI is forcing a fundamental rethink of how work gets done, the life sciences industry is grappling with a deeper question: what role should human creativity play in an increasingly [...]
New $60 Blood Test Detects Lung Cancer Without Costly DNA Sequencing
A simple blood test that detects chemical changes in DNA identified more than 90% of stage 2-4 lung cancers in an early study, without relying on costly DNA sequencing. Researchers at Tel Aviv University and collaborating [...]
Reducing drug development failures with human-relevant models and AI
Professor Joseph C. Wu of Stanford University explains how stem cells, human-relevant models and AI are helping researchers predict which drug candidates are most likely to succeed before clinical trials. Researchers now have access [...]
Half of vaccines are binned – ‘fridge-free’ versions could change that
Vaccines that do not need to be kept cool in a fridge have been successfully trialed in patients for the first time, say UK scientists. Currently, most vaccines need to be refrigerated or frozen [...]
Mushroom Mystery: The Fungus That Makes People See Tiny Humans
A mushroom sold in markets and served in restaurants in Southwest China has an unusual warning attached to it: cook it thoroughly, or you may start seeing tiny people. For decades, people have reported [...]
Artificial intelligence used to design brand new viruses
Artificial Intelligence has been used to design brand new viruses that are fully functional and can replicate in the laboratory, say US researchers. It is the first time whole genomes have been successfully designed [...]
Molecular Manufacturing: The Future of Nanomedicine – New book from NanoappsMedical Inc.
This book explores the revolutionary potential of atomically precise manufacturing technologies to transform global healthcare, as well as practically every other sector across society. This forward-thinking volume examines how envisaged Factory@Home systems might enable the cost-effective [...]
Moderna kicks off Phase I Ebola trial as Africa readies itself for research
If the Phase I trial is successful, Moderna plans to quickly initiate Phase II and Phase III trials of its Ebola vaccine. Moderna has initiated a Phase I trial of its mRNA Ebola vaccine [...]
3D Human Brain Tissue Model Replicates Alzheimer’s Pathology
Summary: Researchers introduced a highly reproducible three-dimensional human brain tissue model capable of replicating complex neurodegenerative processes in Alzheimer’s disease. Developed over nine years using human stem cells, the self-organizing tissue spheroids integrate functional neurons, [...]















