Immune Aspects of Biopharmaceuticals and Nanomedicines
1st Edition
Raj Bawa, Janos Szebeni, Thomas J Webster, Gerald F. Audette
The enormous advances in the immunology of biotherapeutics and nanomedicines in the past two decades have necessitated an authoritative and comprehensive reference that can be relied upon by immunologists, biomedical researchers, physicians, pharmaceutical and formulation scientists, clinicians, regulatory personnel, technology transfer officers, venture capitalists, and policy makers alike.
Table of Contents
Proteins as Medicines: The Era of Biologics
Raj Bawa, János Szebeni, Thomas J. Webster, and Gerald F. Audette
Immunological Issues with Medicines of Nano Size: The Price of Dimension Paradox
János Szebeni and Raj Bawa
Immunotherapy and Vaccines
Johanna Poecheim and Gerrit Borchard
Emerging Trends in Delivery of Novel Vaccine Formulations
Trinh Phuong Vo, Rikhav P. Gala, Thripthy Chandran, Sucheta D’Sa, and Ruhi V. Ubale
Current Understanding of Interactions between Nanoparticles and the Immune System
Marina A. Dobrovolskaia, Michael Shurin, and Anna A. Shvedova
Auto-antibodies as Biomarkers for Disease Diagnosis
Angelika Lueking, Heike Göhler, and Peter Schulz-Knappe
The Accelerated Blood Clearance Phenomenon of PEGylated Nanocarriers
Amr S. Abu Lila and Tatsuhiro Ishida
Anti-PEG Immunity Against PEGylated Therapeutics
Amr S. Abu Lila and Tatsuhiro Ishida
Complement Activation: Challenges to Nanomedicine Development
Dennis E. Hourcade, Christine T. N. Pham, and Gregory M. Lanza
Intravenous Immunoglobulin at the Borderline of Nanomedicines and Biologicals: Antithrombogenic Effect via Complement Attenuation
Milan Basta
Lessons Learned from the Porcine CARPA Model: Constant and Variable Responses to Different Nanomedicines and Administration Protocols
Rudolf Urbanics, Péter Bedőcs, and János Szebeni
Blood Cell Changes in Complement Activation-Related Pseudoallergy: Intertwining of Cellular and Humoral Interactions
Zsófia Patkó and János Szebeni
Immune Reactions in the Delivery of RNA Interference-Based Therapeutics: Mechanisms and Opportunities
Kaushik Thanki, Emily Falkenberg, Monique Gangloff, and Camilla Foged
Lipid Nanoparticles Technology Induced Immunomodulatory Effects of siRNA
Ranjita Shegokar and Prabhat Mishra
Nanovaccines against Intracellular Pathogens Using Coxiella burnetii as a Model Organism
Erin J. van Schaik, Anthony E. Gregory, Gerald F. Audette, and James E. Samuel
Immunogenicity Assessment for Therapeutic Protein Products
FDA
Assay Development and Validation for Immunogenicity Testing of Therapeutic Protein Products: Guidance for Industry
FDA
The “Sentinel”: A Nanomedical Strategy for Radical Immune System Enhancement
Frank Boehm and Angelika Domschke
Immunotherapy for Gliomas and Other Intracranial Malignancies
Mario Ganau, Gianfranco K. I. Ligarotti, Salvatore Chibbaro, and Andrea Soddu
Liposome-Induced Complement Activation-Related Pseudoallergy
Amr S. Abu Lila, Janos Szebeni, and Tatsuhiro Ishida
Available now at CRC Press
Image Credit: Alias Studio Sydney
News This Week
Shaping nanoparticles for improved quantum information technology
Particles that are mere nanometers in size are at the forefront of scientific research today. They come in many different shapes: rods, spheres, cubes, vesicles, S-shaped worms and even donut-like rings. What makes them [...]
Nanoscale manipulation of light leads to exciting new advancement
Controlling the interactions between light and matter has been a long-standing ambition for scientists seeking to develop and advance numerous technologies that are fundamental to society. With the boom of nanotechnology in recent years, [...]
Jamilee Baroud Podcast – Frank Boehm (NA Founder) Interview
In her inaugural podcast, Jamilee interviews Frank Boehm of NanoApps Medical Inc and NanoApps Athletics Inc. From Jamilee's podcast: Welcome to the first episode of "In a Click". On todays show I chat with [...]
NanoApps Athletics Inc. Established
Frank Boehm (NanoApps Medical Inc. founder) and Amanda Scott (NA CEO) join NanoApps Athletics Inc. NanoApps Athletics Inc proposes a unique synergistic biochemical/nanomedical strategy for the expedited repair and healing of Achilles tendon micro [...]
Use of nanopores could lead to cleaner water
Not all nanopores are created equal. For starters, their diameters vary between 1 and 10 nanometers (nm). The smallest of these nanopores, called Single Digit Nanopores (SDNs), have diameters of less than 10 nm [...]
Light in a new light
In a paper published in Nature's NPJ Quantum Information ("Multiphoton quantum-state engineering using conditional measurements"), Omar Magaña-Loaiza, assistant professor in the Louisiana State University (LSU) Department of Physics & Astronomy, and his team of [...]
Google researchers have reportedly achieved “quantum supremacy”
According to a report in the Financial Times, a team of researchers from Google led by John Martinis have demonstrated quantum supremacy for the first time. This is the point at which a quantum [...]
Brain-computer interfaces without the mess
It sounds like science fiction: controlling electronic devices with brain waves. But researchers have developed a new type of electroencephalogram (EEG) electrode that can do just that, without the sticky gel required for conventional [...]
Scientists create a nanomaterial that is both twisted and untwisted at the same time
A new nanomaterial developed by scientists at the University of Bath could solve a conundrum faced by scientists probing some of the most promising types of future pharmaceuticals (Nanoscale Horizons, "Measuring optical [...]
Artificial intelligence helps to predict hybrid nanoparticle structures
Researchers at the Nanoscience Center and Faculty of Information Technology in the University of Jyväskylä, Finland, have achieved a significant step forward in predicting atomic structures of hybrid nanoparticles. A research article published in [...]
Creating new opportunities from nanomaterials
A hundred years ago, “2d” meant a two-penny, or 1-inch, nail. Today, “2-D” encompasses a broad range of atomically thin flat materials, many with exotic properties not found in the bulk equivalents of the [...]
Nanomedical Device and Systems Design: Challenges, Possibilities, Visions now available to rent on Kindle
To accommodate students who wish to read the book at an affordable cost, Nanomedical Device and Systems Design: Challenges, Possibilities, Visions by Frank Boehm (CEO NanoApps Medical Inc.) is available to rent on Kindle. This book benefits [...]
Colour-change urine test for cancer shows potential in mouse study
Tools that detect cancer in its early stages can increase patient survival and quality of life. However, cancer screening approaches often call for expensive equipment and trips to the clinic, which may not be [...]
Ma vs Musk: tech tycoons spar on future of AI
Jack Ma believes artificial intelligence poses no threat to humanity, but Elon Musk called that "famous last words" as the billionaire tech tycoons faced off Thursday in an occasionally animated debate on futurism in [...]
Nanodiamonds as platform for therapy and diagnosis of brain diseases
The blood-brain barrier is a physiological boundary layer that works highly selectively and thus protects the brain: On the one hand, pathogens or toxins are effectively prevented from penetrating the brain, on the other [...]
Carbon nanotube breathalyzer can detect marijuana
As recreational marijuana legalization becomes more widespread throughout the U.S., so has concern about what that means for enforcing DUI laws. Unlike a breathalyzer used to detect alcohol, police do not have a device [...]
Leave A Comment