An international team led by scientists at the University of Sydney has demonstrated nanowire networks can exhibit both short- and long-term memory like the human brain.
“In this research we found higher-order cognitive function, which we normally associate with the human brain, can be emulated in non-biological hardware,” Dr. Loeffler said.
“This work builds on our previous research in which we showed how nanotechnology could be used to build a brain-inspired electrical device with neural network-like circuitry and synapse-like signaling.
“Our current work paves the way towards replicating brain-like learning and memory in non-biological hardware systems and suggests that the underlying nature of brain-like intelligence may be physical.”
Nanowire networks are a type of nanotechnology typically made from tiny, highly conductive silver wires that are invisible to the naked eye, covered in a plastic material, which are scattered across each other like a mesh. The wires mimic aspects of the networked physical structure of a human brain.

Advances in nanowire networks could herald many real-world applications, such as improving robotics or sensor devices that need to make quick decisions in unpredictable environments.
“This nanowire network is like a synthetic neural network because the nanowires act like neurons, and the places where they connect with each other are analogous to synapses,” senior author Professor Zdenka Kuncic, from the School of Physics, said.
“Instead of implementing some kind of machine learning task, in this study Dr. Loeffler has actually taken it one step further and tried to demonstrate that nanowire networks exhibit some kind of cognitive function.”
To test the capabilities of the nanowire network, the researchers gave it a test similar to a common memory task used in human psychology experiments, called the N-Back task.
For a person, the N-Back task might involve remembering a specific picture of a cat from a series of feline images presented in a sequence. An N-Back score of 7, the average for people, indicates the person can recognize the same image that appeared seven steps back.
“What we did here is manipulate the voltages of the end electrodes to force the pathways to change, rather than letting the network just do its own thing. We forced the pathways to go where we wanted them to go,” Dr. Loeffler said.
“When we implement that, its memory had much higher accuracy and didn’t really decrease over time, suggesting that we’ve found a way to strengthen the pathways to push them towards where we want them, and then the network remembers it.
“Neuroscientists think this is how the brain works, certain synaptic connections strengthen while others weaken, and that’s thought to be how we preferentially remember some things, how we learn and so on.”
The researchers said when the nanowire network is constantly reinforced, it reaches a point where that reinforcement is no longer needed because the information is consolidated into memory.
“It’s kind of like the difference between long-term memory and short-term memory in our brains,” Professor Kuncic said.
“If we want to remember something for a long period of time, we really need to keep training our brains to consolidate that, otherwise it just kind of fades away over time.
“One task showed that the nanowire network can store up to seven items in memory at substantially higher than chance levels without reinforcement training and near-perfect accuracy with reinforcement training.”
News
Cancer’s Hidden Antioxidant Shield Helps It Escape the Immune System
Blocking an antioxidant protein that tumors use to suppress immune attacks improved cancer immunotherapy responses in mice. Cancer cells can release antioxidants that interfere with the immune cells trying to kill them. Researchers have [...]
Scientists Find a Berry Compound That Helps Muscle Cells Burn Fat
Pterostilbene, a compound found naturally in some foods, affects how skeletal muscles process fats by stabilizing a protein called PPARδ and increasing its signaling activity. Pterostilbene, a natural compound found in blueberries, grapes, and [...]
Two Hidden Forces Help Build the Human Brain Before Birth
Scientists have uncovered two surprising forces that help guide how the human brain forms before birth. Before birth, the human brain is shaped in large part by an unusual class of stem cells known [...]
Researchers Uncover a Hidden Trigger Behind Chronic Inflammation
The findings offer new insights that could help guide the development of future therapies. A protein called human resistin may help flip on one of the immune system’s most powerful inflammatory switches. Researchers at [...]
Scientists Have Uncovered Previously Hidden Microbial Activity on Human Skin
The most abundant microbes on your skin may not be the ones doing most of the work. Human skin supports vast communities of bacteria, fungi, and viruses that can influence its protective barrier, immune [...]
Brazilian Tree Compounds Fight COVID-19 on Multiple Fronts
Scientists found compounds in a Brazilian tree that hit SARS-CoV-2 on multiple fronts, revealing a promising new lead in the search for COVID-19 treatments. Researchers have found that galloylquinic acids extracted from the leaves [...]
Cutting Two Amino Acids Slowed Prostate Cancer in Mice
A newly identified link between amino acid metabolism and cholesterol production may help prostate tumors adapt to hormone therapy. Prostate cancer can find ways around treatments designed to deprive tumors of the hormones they [...]
Largest-Ever Physics Survey Raises New Doubts About Our Model of the Universe
Physicists around the world remain deeply divided on key mysteries of the universe, from dark matter to quantum gravity. The standard cosmological model failed to gain majority support, and no leading theory dominated the [...]
Scientists Just Overturned a 100-Year-Old Belief About Bacteria in the Lungs
New findings raise questions about the role of microbes living in the lungs. More than 35 trillion bacteria live throughout the human body, forming microbiomes in the gut, mouth, lungs, skin, and urogenital tract. [...]
GHCE Concept
From the preface of the book Global Health Care Equivalency in the Age of Nanotechnology, Nanomedicine and Artificial Intelligence, Edited by Frank Boehm: Since the publication of my first book (Nanomedical Device and Systems [...]
Novartis, Ionis drug failure spurs questions
Pelacarsen didn’t protect heart health despite lowering levels of a protein particle, “Lp(a),” in a large clinical trial — a result with important implications for cardiovascular drug research. Dive Brief: An RNA drug from [...]
New injectable treatment helps the brain rebuild after stroke
Biomedical engineers at Duke University have created an injectable biomaterial that may help the brain recover from damage left behind by an ischemic stroke. In experiments with mice, the material transformed the cavity created [...]
Scientists Discover a Hidden “Immune Organ” Inside the Skull
Researchers discovered lymph node-like immune hubs inside skull bone marrow that appear to act as rapid-response centers for the brain. For decades, the brain was thought to operate largely apart from the immune system. [...]
Engineered tRNAs and lipid nanoparticles target nonsense mutation cystic fibrosis
Researchers have developed a potential new approach for treating a form of cystic fibrosis caused by so-called nonsense mutations, combining chemically modified transfer RNAs with lipid nanoparticles designed to deliver the therapy directly to [...]
New pancreatic cancer drug carries a $39,800 monthly list price
A groundbreaking treatment for one of the most common forms of pancreatic cancer has been approved in pill form by the FDA. Revolution Medicines’ oral tablet daraxonrasib, branded as Rasonque, reduced the risk of [...]
Researchers Have Discovered a New Way To Reduce Chronic Nerve Pain
A cancer-linked protein called BRAF may help drive chronic nerve pain, and existing cancer drugs targeting it reduced pain sensitivity in preclinical models. Chronic nerve pain can persist long after an injury and often [...]















