Doctors experimenting with AI tools to help diagnose patients is nothing new. But getting them to trust the AIs they’re using is another matter entirely.
To establish that trust, researchers at Cornell University attempted to create a more transparent AI system that works by counseling doctors in the same way a human colleague would — that is, arguing over what the medical literature says.







Their resulting study, which will be presented at the Association for Computing Machinery Conference on Human Factors in Computing Systems later this month, found that how a medical AI works isn’t nearly as important to earning a doctor’s trust as the sources it cites in its suggestions.
“A doctor’s primary job is not to learn how AI works,” said Qian Yang, an assistant professor of information science at Cornell who led the study, in a press release. “If we can build systems that help validate AI suggestions based on clinical trial results and journal articles, which are trustworthy information for doctors, then we can help them understand whether the AI is likely to be right or wrong for each specific case.”
“We built a system that basically tries to recreate the interpersonal communication that we observed when the doctors give suggestions to each other, and fetches the same kind of evidence from clinical literature to support the AI’s suggestion,” Yang said.
The AI tool Yang’s team created is based on GPT-3, an older large language model that once powered OpenAI’s ChatGPT. The tool’s interface is fairly straightforward: on one side, it provides the AI’s suggestions. The other side contrasts this with relevant biomedical literature the AI gleaned, plus brief summaries of each study and other helpful nuggets of information like patient outcomes.
So far, the team has developed their tool with three different medical specializations: neurology, psychiatry, and palliative care. When the doctors tried the versions tailored to their respective field, they told the researchers that they liked the presentation of the medical literature, and affirmed they preferred it to an explanation of how the AI worked.
Either way, this specialized AI seems to be faring better than ChatGPT’s attempt of playing the doctor in a larger study, which found that 60 percent of its answers to real medical scenarios disagreed with human experts’ opinions or were too irrelevant to be helpful.
But the jury is still out on how the Cornell researchers’ AI would hold up when subjected to a similar analysis.
Overall, it’s worth noting that while these tools may be helpful to doctors who have years of expertise to inform their decisions, we’re still a very long way out from an “AI medical advisor” that can replace them.
News
Cancer’s Hidden Antioxidant Shield Helps It Escape the Immune System
Blocking an antioxidant protein that tumors use to suppress immune attacks improved cancer immunotherapy responses in mice. Cancer cells can release antioxidants that interfere with the immune cells trying to kill them. Researchers have [...]
Scientists Find a Berry Compound That Helps Muscle Cells Burn Fat
Pterostilbene, a compound found naturally in some foods, affects how skeletal muscles process fats by stabilizing a protein called PPARδ and increasing its signaling activity. Pterostilbene, a natural compound found in blueberries, grapes, and [...]
Two Hidden Forces Help Build the Human Brain Before Birth
Scientists have uncovered two surprising forces that help guide how the human brain forms before birth. Before birth, the human brain is shaped in large part by an unusual class of stem cells known [...]
Researchers Uncover a Hidden Trigger Behind Chronic Inflammation
The findings offer new insights that could help guide the development of future therapies. A protein called human resistin may help flip on one of the immune system’s most powerful inflammatory switches. Researchers at [...]
Scientists Have Uncovered Previously Hidden Microbial Activity on Human Skin
The most abundant microbes on your skin may not be the ones doing most of the work. Human skin supports vast communities of bacteria, fungi, and viruses that can influence its protective barrier, immune [...]
Brazilian Tree Compounds Fight COVID-19 on Multiple Fronts
Scientists found compounds in a Brazilian tree that hit SARS-CoV-2 on multiple fronts, revealing a promising new lead in the search for COVID-19 treatments. Researchers have found that galloylquinic acids extracted from the leaves [...]
Cutting Two Amino Acids Slowed Prostate Cancer in Mice
A newly identified link between amino acid metabolism and cholesterol production may help prostate tumors adapt to hormone therapy. Prostate cancer can find ways around treatments designed to deprive tumors of the hormones they [...]
Largest-Ever Physics Survey Raises New Doubts About Our Model of the Universe
Physicists around the world remain deeply divided on key mysteries of the universe, from dark matter to quantum gravity. The standard cosmological model failed to gain majority support, and no leading theory dominated the [...]
Scientists Just Overturned a 100-Year-Old Belief About Bacteria in the Lungs
New findings raise questions about the role of microbes living in the lungs. More than 35 trillion bacteria live throughout the human body, forming microbiomes in the gut, mouth, lungs, skin, and urogenital tract. [...]
GHCE Concept
From the preface of the book Global Health Care Equivalency in the Age of Nanotechnology, Nanomedicine and Artificial Intelligence, Edited by Frank Boehm: Since the publication of my first book (Nanomedical Device and Systems [...]
Novartis, Ionis drug failure spurs questions
Pelacarsen didn’t protect heart health despite lowering levels of a protein particle, “Lp(a),” in a large clinical trial — a result with important implications for cardiovascular drug research. Dive Brief: An RNA drug from [...]
New injectable treatment helps the brain rebuild after stroke
Biomedical engineers at Duke University have created an injectable biomaterial that may help the brain recover from damage left behind by an ischemic stroke. In experiments with mice, the material transformed the cavity created [...]
Scientists Discover a Hidden “Immune Organ” Inside the Skull
Researchers discovered lymph node-like immune hubs inside skull bone marrow that appear to act as rapid-response centers for the brain. For decades, the brain was thought to operate largely apart from the immune system. [...]
Engineered tRNAs and lipid nanoparticles target nonsense mutation cystic fibrosis
Researchers have developed a potential new approach for treating a form of cystic fibrosis caused by so-called nonsense mutations, combining chemically modified transfer RNAs with lipid nanoparticles designed to deliver the therapy directly to [...]
New pancreatic cancer drug carries a $39,800 monthly list price
A groundbreaking treatment for one of the most common forms of pancreatic cancer has been approved in pill form by the FDA. Revolution Medicines’ oral tablet daraxonrasib, branded as Rasonque, reduced the risk of [...]
Researchers Have Discovered a New Way To Reduce Chronic Nerve Pain
A cancer-linked protein called BRAF may help drive chronic nerve pain, and existing cancer drugs targeting it reduced pain sensitivity in preclinical models. Chronic nerve pain can persist long after an injury and often [...]















