Drug cancer cell treatment, Doxil, manufactured by Ayana Pharma, was launched a week ago, to the International Space Station, as part of the mission of SpaceX. The launch of the drug was made possible by SpacePharma, an Israeli start-up laboratory.
Certainly a cosmic breakthrough in the field of Space, this latest development could impact the treatment of drugs against cancer.
Doxil Nanotechnology Drug
A week ago, the pioneering study was launched without any intended witticism. The Falcon 9 launcher of SpaceX carried an extremely sophisticated laboratory that SpacePharma developed.
Their space laboratory is shrunk or mini version of the technology utilized for regular testing, although it weighs only four kilograms. It allows for more remote-controlled, actual-time testing to be carried out in space.
The objective of the study was to test if the cancer treatment, a nanotechnology drug that Ayana Pharma developed to treat cancer, would change in zero-gravity conditions. The study authors wanted to find out the drug itself or its actions against cancer cells would change the celestial space.
Essentially, Doxil is a complex-structure liposome drug formulated to treat ovarian cancer, several myelomas, or bone marrow cancer, as well as other contraindications.
The complex and unique structure of the drug makes it possible to test whether conditions of non-gravity, as they exist in space, affect the physical properties of the drug and its activity against cancer cells.
Probable Changes in the Nanoparticle Drug Investigated
Since the chemical and physical properties of Doxil and the cancer cell may differ under gravitational circumstances, the study authors will seek to investigate if there are changes in the nanoparticle, acceptance into cancer cells, the active substance that combats cancer cells, as well as its rate of discharge, and the drug’s distinctive envelope properties.
The notion behind this study is certainly to understand better the aspects of the drug, as it may specify a future probability of the efficacy in conditions of non-gravity.
The development of Doxil, detailed in the Chemocare site, was led by the Hebrew University’s Professor Yehezel Bernholtz, who, in 2012, founded Ayana Pharma.
The professor is recognized as a global expert in nanotechnology therapeutics, as Doxil was the first nanotechnology drug of the world approved by the Food and Drug Administration, as reported in the Fierce Pharma site.
His pharmaceutical firm focuses on both the development and production of liposomal drugs for cancer treatment, not just for cancer but also for other diseases.
Scientists from the Terasaki Institute for Biomedical Innovation (TIBI) have developed a contact lens that can capture and detect exosomes, nanometer-sized vesicles found in bodily secretions which have the potential for being diagnostic cancer [...]
Among the total number of deaths caused by different types of cancer, esophageal cancer is the sixth most significant. Several conventional treatments, such as radiotherapy, chemotherapy, and surgery have multiple side effects, including off-target [...]
Cell membrane-coated nanoparticles, applied in targeted drug delivery strategies, combine the intrinsic advantages of synthetic nanoparticles and cell membranes. Although stem cell-based delivery systems were highlighted for their targeting capability in tumor therapy, inappropriate [...]
When babies in the African countries of Guinea Bissau and Uganda were given the tuberculosis vaccine, something remarkable happened. Instead of the vaccine only protecting against the target bacteria – Myocbacterium tuberculosis – the tuberculosis vaccine offered broad protection against a [...]
Thousands of years ago, across the Eastern Mediterranean, multiple Bronze Age civilizations took a distinct turn for the worse at around the same time. The Old Kingdom of Egypt and the Akkadian Empire both collapsed, and there was [...]
IN OCTOBER 2014, virologist Edward Holmes took a tour of the Huanan Seafood Wholesale Market in Wuhan, a once relatively overlooked city of about 11 million people in the central Chinese province of Hubei. The market would [...]
Self-healable ionic sensing materials with fatigue resistance are imperative in robotics and soft electronics for extended service life. The existing artificial ionic skins with self-healing capacity were prepared by network reconfiguration, constituting low-energy amorphous [...]
As demand for solar energy rises around the world, scientists are working to improve the performance of solar devices—important if the technology is to compete with traditional fuels. But researchers face theoretical limits on [...]
When shrimp shell nanoparticles were mixed into cement paste, the material became substantially stronger — researchers propose an innovation that could lead to less seafood waste and fewer carbon dioxide emissions from concrete production. [...]
A black-and-white video shared on social media showed a microscopic corkscrew-shaped helix as it appeared to consume a sperm, transport it, and ultimately lead the little swimmer into the wall of an [...]
Polymers containing quantum dots (QDs) are considered crucial components of next-generation consumer items, but ambiguity remains regarding how these compounds may negatively affect public health and the environment. A pre-proof paper from the Journal of Hazardous [...]
A new copper coating that kills bacteria quicker and in greater amounts than current formulations could soon be available for hospitals and other high-traffic facilities. Although current formulations made of pure copper are antibacterial [...]
A vaccination as tumor therapy - with a vaccine individually created from a patient's tissue sample that " attaches" the body's own immune system to cancer cells: the basis for this long-term vision has [...]
Although retinoic acid (RA) can induce cell death, its weak anticancer efficacy limits its clinical applications. To this end, stimulus-responsive self-assembling prodrug-based nanomedicines are promising candidates that enable controlled drug delivery. In an article [...]
Graphene is a multifunctional carbon nanomaterial widely synthesized for its applications in composites, energy storage, and sensors. Although previous reviews mentioned that achieving an increased yield compromises graphene quality, limiting its commercialization, recent research [...]
A new COVID variant has recently been detected in several countries including the UK, US, India, Australia and Germany. Called BA.2.75, it’s a subvariant of omicron. You might have also heard it called “Centaurus”, the [...]