September 23 2017

About NanoApps Medical Inc

NanoApps Medical, Inc. was incorporated in 2009 with the goal of developing advanced nanomedical diagnostic and therapeutic technologies for the benefit of individuals across both the developing and developed worlds.

The larger picture will be to eventually attain a situation of “Global Health Care Equivalency” (GHCE) where any individual on the planet may have access to the same advanced, high quality, and cost effective nanomedical diagnostic and therapeutic technologies, no matter where they happen to reside, or under what conditions they live. Boehm is now compiling a book that will articulate this grand vision.

Further, NanoApps Medical is ambitiously aiming to transition terrestrial nanomedicine to space applications to facilitate future Lunar and Mars missions, such as those being boldly planned by NASA and SpaceX.

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Potential Nanomedical Countermeasures to Mitigate the Effects of Space on Humans

Incremental progress has been made on several fronts that may employ nanomedical strategies, to potentially counteract the deleterious effects of galactic cosmic rays and microgravity on human physiology.  The implementation of these strategies and the enhancement of their preventative, diagnostic, or therapeutic effects for future orbital, planetary, and deep space missions might be enabled via diverse and potent synergies between unique nanomedical applications of nanomaterials and nanotechnologies.

 

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NanoApps Medical, Inc. Aiming to Develop Nanobiosensor for Malaria, Ebola, and Zika

NanoApps Medical, Inc. (Vancouver, Canada) is working to develop a point of care diagnostic nanobiosensor platform for the detection of Malaria via saliva samples, which may be reconfigured to detect Ebola, and Zika. The use of this nanobiosensor will be far less invasive and safer than through the extraction of blood samples, while conveying more rapid results.

The current gold standard for the detection of Malaria is blood smear microscopy, the results of which may take from many hours to several days to determine. This test also has the requirements of technical expertise in blood sample preparation, and a trained microscopist. Hence, the proposed nanobiosensor would be a significant improvement in terms of expediting and simplifying the diagnosis of Malaria, Ebola, and Zika in that it would be easy to administer, and provide rapid and clearly understandable results.

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Frank Boehm represents Alias Studio Sydney in North America

From Alias Studio Sydney:

To better serve our new Aerospace, Nanotechnology, and Nanomedicine clients we are pleased to engage Frank Boehm of Vancouver Canada to represent Alias in North America.

A true entrepreneur and author of the respected reference book: Nanomedical Device and Systems Design: Challenges, Possibilities, Visions, Frank is the CEO of NanoApps Medical Inc.

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Nanomedical Device and Systems Design: Challenges, Possibilities, Visions by Frank Boehm

Nanomedical Device and Systems Design: Challenges, Possibilities, Visions by Frank Boehm of NanoApps Medical Inc. serves as a preliminary guide toward the inspiration of specific investigative pathways that may lead to meaningful discourse and significant advances in nanomedicine/nanotechnology.

This volume considers the potential of future innovations that will involve nanomedical devices and systems. It endeavors to explore remarkable possibilities spanning medical diagnostics, therapeutics, and other advancements that may be enabled within this discipline.

In particular, this book investigates just how nanomedical diagnostic and therapeutic devices and systems might ultimately be designed and engineered to accurately diagnose and eradicate pathogens, toxins, and myriad disease states.

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Nanotechnology, Nanomedicine, and AI: Toward the Dream of Global Health Care Equivalency

Synergies between nanotechnology, nanomedicine, and AI may enable this vision on a global scale. Progress toward this goal will be incremental, with each successive wave of nanomedical technologies being more advanced than the previous wave. The tipping point will arrive with the emergence of Molecular Manufacturing (MM)which will make possible the economical fabrication of the types of advanced autonomous nanomedical devices that are described in Frank’s initial book: Nanomedical Device and Systems Design: Challenges, Possibilities, Visions

NanoApps Medical keenly recognizes that such a massive undertaking on a global scale will require intense and high spirited collaboration with like minded individuals, research labs, institutions, organizations, and government agencies worldwide for its realization. It will also require significant resources and time.

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News

A New Mechanism For Controlling Memory

From an article at neurosciencenews.com: Summary: Study reveals receptor movement is essential for synaptic plasticity as a response to neural activity. Halting receptor movement may block specific memory acquisition, researchers report, thus confirming the role [...]

Nanogel-encapsulated stem cells for heart attack patients

Heart disease and heart-related illnesses are a leading cause of death around the world, but treatment options are limited. Now, one group reports in ACS Nano ("Heart Repair Using Nanogel-Encapsulated Human Cardiac Stem Cells in [...]

3D Graphene-Acrylamide Hydrogel Scaffolds for Neuron Growth

From an article by Liam Critchley at AZonano.com: The design of nanostructured scaffolds has gathered a significant amount of interest over the last few years in nanomedicine and tissue engineering fields. Within the design of [...]

Nanochip could heal injuries or regrow organs with one touch

A novel device that reprograms skin cells could represent a breakthrough in repairing injured or ageing tissue, researchers say. The new technique, called tissue nanotransfection, is based on a tiny device that sits on the [...]

FDA Breaks New Ground With First Approved Gene Therapy for Cancer

When oncologist Dr. Carl June heard the Food and Drug Administration’s decision to bring the first gene therapy to market in the US, he pinched himself, hard. “It was so improbable that this would ever [...]

The big one is coming, and it’s going to be a flu pandemic

By Dr. Sanjay Gupta, Chief Medical Correspondent CNN: Experts say we are "due" for one. When it happens, they tell us, it will probably have a greater impact on humanity than anything else currently happening in [...]

Scientists aim to find out how lung cells react in space

Space travel can cause a lot of stress on the human body as the change in gravity, radiation and other factors creates a hostile environment. While much is known about how different parts of the [...]

Argonne Supercomputer Aims to Map All the Neurons in the Brain

From a post by Michael Feldman : Researchers at Argonne National Laboratory are going to be using the Theta supercomputer to generate a map of all the neural connections in a brain. According to a news [...]

Potential Nanomedical Countermeasures to Mitigate the Effects of Space on Humans

Incremental progress has been made on several fronts that may employ nanomedical strategies, to potentially counteract the deleterious effects of galactic cosmic rays and microgravity on human physiology. The implementation of these strategies and the [...]

Test Strips with Platinum-Coated Gold Nanoparticles for Better Cancer Detection

A home pregnancy test is the most common test strip for diagnosis. Pregnant women have progressively increasing levels of the biomarker human chorionic gonadotropin (hCG), which is easily traceable in urine. A thin, colorful strip [...]

Nanotechnology, Nanomedicine, and AI: Toward the Dream of Global Health Care Equivalency

It is envisaged that nanomedicine, beyond the amazing possibilities that may materialize over the next 10-30 years toward advanced diagnostic and therapeutic capacities, might have a far more extensive role than to supplant existing medical [...]

Biophysics study makes exciting advancements for the future of DNA sequencing

A Northeastern research team has developed new technology that optimizes DNA sequencing using nanophysics and electric currents. In a paper published in Nature Nanotechnology, Northeastern Professor of Biological Physics Meni Wanunu, in partnership with Pacific [...]

NanoApps Medical Inc. Near-Term Projects

NanoApps Medical is aiming to investigate the possibility that superparamagnetic nanoparticles (SPIONs) and other classes of nanoparticles (e.g., gold coated nanoshells) might have the capacity to target cancerous tumors, metastasizing cancer cells, pathogens, etc. to deactivate/eliminate them via hypothermia.

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NanoMedicine and Human Spaceflight

Future nanomedical devices and systems will have strong potential to enable a broad range of aerospace and space applications. With further dimensional reductions in conjunction with the increased capabilities of nanoelectronics and artificial intelligence (AI), nanomedicine may facilitate the development of a wide array of advanced nanomedical diagnostic and therapeutic capabilities dedicated to the health and well being of future astronauts and space pioneers, the inhabitants of future Lunar and Mars colonies, and deep space explorers.

 

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Ocular and Cellular Anomalies

Microgravity induced ophthalmic anomalies were observed by Mader et al in seven astronauts who were involved in long-duration (six month) space missions to the ISS. An additional 300 astronauts were asked to complete a questionnaire in regard to in-flight vision changes. For the seven astronauts under study, the ophthalmic results indicated disk edema (in five), globe flattening (in five), choroidal folds (in five), cotton wool spots (in three), nerve fiber layer thickening (in six), decreased near-vision (in six). Further, optic nerve sheath distension and tortuous optic nerves were observed.

Of the 300 questionnaire respondents, 60% of the astronauts who were engaged in long duration missions reported experiencing degradation in both their near and distance vision; these conditions persisted for years postflight for some individuals.

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Cardiac Function and Muscle Atrophy

In 2004, NASA released its Bioastronautics Critical Path Roadmap (BCPR), with an aim to “establish tolerance limits to the space environment and develop countermeasures to overcome these problems.” The BCPR listed close to 50 space-related medical risk factors, which included those associated with the potential for serious cardiac dysrhythmias (from unknown causes) that may lead to hypotension (low blood pressure) and syncope (fainting). Further, significant cardiac rhythm issues (e.g., ventricular tachycardia – rapid heartbeat), linked with altered cardiac electrical activity and stability were reported for a number of cases during a MIR mission.

Degraded cardiac and vascular functionality, as well as decreased cardiac mass can result from both short and long duration spaceflight.

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