Researchers at Penn Medicine have discovered a new, more effective method of preventing the body's own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy's effectiveness. When injected into the bloodstream, unmodified nanoparticles are swarmed by elements of the immune [...]
Bioinspired by tunicates and mussels, a Korean research team has created a “bomb-like” anticancer therapeutic agent that only destroys cancer cells. Schematic diagram of the mechanism of action of photoactivatable adhesive nanobombs made with bioinspired strategies from marine tunicates and mussels. (Image Credit: POSTECH). The nanobomb produces heat in precise sites where near-IR (NIR) laser [...]
(Reuters) - “Long COVID”, where symptoms of COVID-19 persist for months after an initial infection, could be emerging as a chronic disease in Finland, Minister of Family Affairs and Social Services Krista Kiuru said on Friday. Speaking at a news conference, she referred to a Finnish expert panel’s summary of more than 4,000 international [...]
The rising concern of plastic pollution and the increase in nanoplastics, which are small plastic debris particles with nanoscale sizes between 1 and 1000 nm, have become a field of research that has garnered popularity over recent years. Innovative research published in the journal, ACS Omega, has investigated the effect of nanoplastics on developing zebrafish [...]
Exciting and novel research has investigated the internalization of nanoparticles by cells to optimize drug delivery into target cells. This research, published within the journal, Pharmaceutics, aims to analyze the simultaneous uptake of two different types of nanoparticles into cells. Enhancing Drug Delivery Using Nanoparticles Nanoparticles, sized within the nanoscale, between 1 and 100 nm, [...]
Does the advent of machine learning mean the classic methodology of hypothesize, predict and test has had its day? Isaac Newton apocryphally discovered his second law – the one about gravity – after an apple fell on his head. Much experimentation and data analysis later, he realised there was a fundamental relationship between force, [...]
A new approach to brain tumor treatment using photodynamic therapy (PDT) with nanotechnology has been explored in a review published in the journal Biomedicines. Unlike radiotherapy and surgical resection, PDT can treat micro-invasive areas and protect critical brain tissue with a high probability of success. Conventional Methods using PDT Photodynamic therapy is a type of phototherapy that [...]
In recent years scientists have worked to create materials that can repair themselves, in order to deal with the swift degradation of devices we use at home. A discovery by Dr. Yehonadav Bekenstein and his team at the Technion could pave the way there. We tend to take it for granted, but the existence [...]
Johns Hopkins Medicine researchers have developed a color-coded test that quickly signals whether newly developed nanoparticles—ultra small compartments designed to ferry medicines, vaccines and other therapies—deliver their cargo into target cells. Historically, nanoparticles have a very low delivery rate to the cytosol, the inside compartment of cells, releasing only about 1%–2% of their contents. [...]
Just when we thought things were looking up at least a little, because the omicron variant, while being more contagious, often takes a milder course than delta, a new variant has emerged. We do not yet know how dangerous it is, or even where it originated. The new variant was detected in early December in a [...]
