Nanotechnology research offers a realistic and efficient method for reducing pesticide waste and enhancing pesticide consumption. A new publication in the journal ACS Agricultural Science & Technology discusses the development of chlorpyrifos-loaded silica nanomaterials enhanced with polydopamine (Cpf-MSNs@PDA) for intelligent pest management.
The release of chlorpyrifos from the hybrid composite was alkali- and heat-dependent, ensuring the effective constituent’s continuous and consistent efficacy over an extended period. The creation of an intelligent nanoparticle for the management of a specific plant diseases generates new ideas for organic farming.
Importance of Pesticides
Pesticides are critical for reducing and managing plant diseases, bugs, and weeds, which are necessary for agricultural production, repairing around 30% of worldwide crop damage. However, more than 90% of conventional pesticides infiltrate the ecosystem during the deposition process, resulting in environmental damage.
Presently, it is believed that developing a controlled-release pesticide technology would efficiently decrease pesticide wastage and increase pesticide consumption. With the advancement of nanomaterials and their widespread use in crop production, several novel pesticide compositions have been created, including nano caplets, nanoliposomes, and nanogels.
Various nanoparticles, including graphene oxide, charcoal, elastomer, and kaolin minerals, have been employed as pesticide carriers so far.
Mesoporous Silica Nanoparticles (MSNs) as Pesticide Carriers
Additionally, the conveniently synthesized surface morphology of MSNs enables the incorporation of adaptable substances or polymeric materials, enabling the development of a nanopesticide delivery mechanism that is responsive to external stimuli (such as pH, illumination, and heat) and thus enables the controlled release of pesticide elements.
Polydopamine (PDA): pH-Responsive Gatekeeper Molecule
To achieve the precise reaction of a nanopesticide to environmental stimuli, the nanocomposite’s surface layer is often altered with reactive gatekeeper molecules. Due to its excellent biological properties, high adhesion, and high photocatalytic effectiveness, polydopamine (PDA), a substance derived from mussels, has garnered significant interest. PDA’s superior film-forming capacity enables it to be uniformly deposited on the exterior of a wide variety of materials for general applications. Additionally, several studies have shown that PDA can be employed as a pH-responsive gatekeeper molecule to regulate drug delivery systems.
Development of an Intelligent Nanopesticide Composite
In this study, the researchers developed a smart nanopesticides compound based on a PDA-modified mesoporous silica nanocomposite (MSN) structure that helps pesticide particles to be released in response to an alkaline stimulus.
Chlorpyrifos (Cpf), a wide-spectrum organophosphate pesticide with dermal contact and gastro toxicity, was chosen as the prototype pesticide due to its widespread usage in farming to control pests. The release rate of Cpf was thoroughly investigated in the presence of pH and other biogenic triggers. Cpf-foliar MSNs@PDA’s adherence, rainfall-runoff tolerance, and pesticide effectiveness were also investigated to determine its durability.
Research Conclusion and Prospect
In conclusion, Cpf-MSNs@PDA, an alkali-triggered nanoscale pesticide combination, was developed in this work. The microporous morphology on the interface of the MSNs was restricted due to the containment of PDA, which limits the extraction efficiency of Cpf into the external environment.
To produce the alkaline-triggered discharge of Cpf-MSNs@PDA, PDA works as a pH-responsive barrier molecule. This novel composite was discovered to have outstanding foliar adherence and great rainfall erosion resistance in simulated testing, indicating that it can significantly prevent pesticide losses due to leaf slippage and rainfall runoff. The presence and degradability of pesticides in the midgut were established by inspection of the gastrointestinal tissue of M. separata, and the probable mechanism of Cpf-MSNs@PDA was established.
This research suggests a viable method for reducing pesticide wastage and contamination in the ecosystem. However, simulated results may not provide accurate physical results. Therefore, field studies should be conducted to improve the efficacy of nanopesticide compounds in the future.
News
New book from NanoappsMedical Inc – Molecular Manufacturing: The Future of Nanomedicine
This book explores the revolutionary potential of atomically precise manufacturing technologies to transform global healthcare, as well as practically every other sector across society. This forward-thinking volume examines how envisaged Factory@Home systems might enable the cost-effective [...]
A Virus Designed in the Lab Could Help Defeat Antibiotic Resistance
Scientists can now design bacteria-killing viruses from DNA, opening a faster path to fighting superbugs. Bacteriophages have been used as treatments for bacterial infections for more than a century. Interest in these viruses is rising [...]
Sleep Deprivation Triggers a Strange Brain Cleanup
When you don’t sleep enough, your brain may clean itself at the exact moment you need it to think. Most people recognize the sensation. After a night of inadequate sleep, staying focused becomes harder [...]
Lab-grown corticospinal neurons offer new models for ALS and spinal injuries
Researchers have developed a way to grow a highly specialized subset of brain nerve cells that are involved in motor neuron disease and damaged in spinal injuries. Their study, published today in eLife as the final [...]
Urgent warning over deadly ‘brain swelling’ virus amid fears it could spread globally
Airports across Asia have been put on high alert after India confirmed two cases of the deadly Nipah virus in the state of West Bengal over the past month. Thailand, Nepal and Vietnam are among the [...]
This Vaccine Stops Bird Flu Before It Reaches the Lungs
A new nasal spray vaccine could stop bird flu at the door — blocking infection, reducing spread, and helping head off the next pandemic. Since first appearing in the United States in 2014, H5N1 [...]
These two viruses may become the next public health threats, scientists say
Two emerging pathogens with animal origins—influenza D virus and canine coronavirus—have so far been quietly flying under the radar, but researchers warn conditions are ripe for the viruses to spread more widely among humans. [...]
COVID-19 viral fragments shown to target and kill specific immune cells
COVID-19 viral fragments shown to target and kill specific immune cells in UCLA-led study Clues about extreme cases and omicron’s effects come from a cross-disciplinary international research team New research shows that after the [...]
Smaller Than a Grain of Salt: Engineers Create the World’s Tiniest Wireless Brain Implant
A salt-grain-sized neural implant can record and transmit brain activity wirelessly for extended periods. Researchers at Cornell University, working with collaborators, have created an extremely small neural implant that can sit on a grain of [...]
Scientists Develop a New Way To See Inside the Human Body Using 3D Color Imaging
A newly developed imaging method blends ultrasound and photoacoustics to capture both tissue structure and blood-vessel function in 3D. By blending two powerful imaging methods, researchers from Caltech and USC have developed a new way to [...]
Brain waves could help paralyzed patients move again
People with spinal cord injuries often lose the ability to move their arms or legs. In many cases, the nerves in the limbs remain healthy, and the brain continues to function normally. The loss of [...]
Scientists Discover a New “Cleanup Hub” Inside the Human Brain
A newly identified lymphatic drainage pathway along the middle meningeal artery reveals how the human brain clears waste. How does the brain clear away waste? This task is handled by the brain’s lymphatic drainage [...]
New Drug Slashes Dangerous Blood Fats by Nearly 40% in First Human Trial
Scientists have found a way to fine-tune a central fat-control pathway in the liver, reducing harmful blood triglycerides while preserving beneficial cholesterol functions. When we eat, the body turns surplus calories into molecules called [...]
A Simple Brain Scan May Help Restore Movement After Paralysis
A brain cap and smart algorithms may one day help paralyzed patients turn thought into movement—no surgery required. People with spinal cord injuries often experience partial or complete loss of movement in their arms [...]
Plant Discovery Could Transform How Medicines Are Made
Scientists have uncovered an unexpected way plants make powerful chemicals, revealing hidden biological connections that could transform how medicines are discovered and produced. Plants produce protective chemicals called alkaloids as part of their natural [...]
Scientists Develop IV Therapy That Repairs the Brain After Stroke
New nanomaterial passes the blood-brain barrier to reduce damaging inflammation after the most common form of stroke. When someone experiences a stroke, doctors must quickly restore blood flow to the brain to prevent death. [...]















