Microorganisms leverage the CRISPR-Cas system as a defense mechanism against viral intrusions. In the realm of genetic engineering, this microbial immune system is repurposed for the targeted modification of the genetic makeup. Under the leadership of Professor Dr. Alexander Probst, microbiologist at the Research Center One Health Ruhr at the Research Alliance Ruhr a [...]
In efforts to tackle the leading cause of blindness in developed countries, researchers have recruited nanotechnology to help regrow retinal cells. Macular degeneration is a form of central vision loss, which has massive social, mobility, and mental consequences. It impacts hundreds of millions of people globally and is increasing in prevalence. The degeneration is the consequence of [...]
Researchers at Tel Aviv University have destroyed 90% of multiple myeloma blood cancer cells under laboratory conditions, and 60% in human tissues taken from patients at Rabin Medical Center (Belinson Hospital), using an RNA-based drug delivered to the cells by targeted lipid nanoparticles. The researchers developed lipid-based nanoparticles (similar to those used in the [...]
Scientists have found a way to use nanotechnology to create a 3D ‘scaffold’ to grow cells from the retina – paving the way for potential new ways of treating a common cause of blindness. Researchers, led by Professor Barbara Pierscionek from Anglia Ruskin University (ARU), have been working on a way to successfully grow retinal pigment [...]
A vaccine that targets inflamed brain cells associated with Alzheimer’s disease could possibly modify or prevent the disease, according to preliminary research. A novel vaccine that targets a protein involved in Alzheimer’s disease helped eliminate toxic cells in mice with the condition. After vaccination, the mice had fewer amyloid plaques and less inflammation in brain tissue [...]
Tiny “dots” that transform light have the potential to drive big advancements. A new material, crafted in the seldom-explored convergence of organic and inorganic chemistry, holds promise to not just enhance the efficiency of solar panels, but also could also usher in the next generation of cancer treatments. Described in a paper published recently [...]
Excessive activation of inflammasomes is associated with various diseases, including gout, Alzheimer's disease, atherosclerosis, and type 2 diabetes. Given the pivotal role of macrophages in both inflammasome activation and nanoparticle phagocytosis, the discovery of anti-inflammatory nanoparticles specifically targeting macrophages could more effectively modulated inflammatory response while minimizing off-target effects in other cell types. However, [...]
A tiny robot that can travel deep into the lungs to detect and treat the first signs of cancer has been developed by researchers at the University of Leeds. The ultra-soft tentacle, which measures just 2 millimeters in diameter and is controlled by magnets, can reach some of the smallest bronchial tubes and could [...]
Scientists have discovered a new way to activate G-protein coupled receptors from inside cells, a breakthrough that helps develop drugs without side effects. Have you ever wondered how drugs reach their targets and achieve their function within our bodies? Imagine the drug molecule or ligand as a message, and the cell membrane receptor serving [...]
Microscopic materials made of clay designed by researchers at the University of Missouri could be key to the future of synthetic materials chemistry. By enabling scientists to produce chemical layers tailor-made to deliver specific tasks based on the goals of the individual researcher, these materials called nanoclays can be used in a wide variety [...]
