In a study published in the journal ACS Applied Materials & Interfaces, a mix of chemistry, nanomaterials, and artificial intelligence (AI) was used to produce a straightforward yet cryptographic anticounterfeiting measure.
The Need for Effective Anticounterfeiting Techniques
The requirement for robust anti-counterfeit solutions is driving scholarly and corporate research to enhance the authenticity and safety of products. The spread of counterfeit commodities is a huge nuisance all over the globe, particularly in the retail and pharmaceutical industries. Fake pharma goods endanger patients and compromise public health, resulting in high economic and social costs for developed as well as developing nations.
To put the magnitude of the issue into perspective, counterfeit medications for treatments of pneumonia and malaria kill roughly 250,000 children annually. Such a significant problem necessitates a serious technical effort to develop powerful anti-counterfeit technologies that are also consistent with market constraints.
Numerous substances and chemical procedures have been suggested as biometric markers. These vary from intricate ink compositions utilized in currency notes to luminous upconverting nano-phosphorous tags, inkjet printable conjugate polymeric platforms, or molecular identifiers like peptides, DNA, and polymers that promise large encoding potentials and secrecy.
These technologies, however, may be cloneable. Moreover, they often need costly hardware and highly skilled workers, restricting their practical uses.
Nanotechnology can Improve PUFs
A highly sophisticated anti-counterfeit technique was provided in this system using physically unclonable functions (PUFs) that are predicated on distinct markers created by chemical procedures in a stochastic mechanism. The unpredictability created by the non-deterministic technique assures that replicating the PUF key is just about impossible whenever the PUF sequence is digitized and saved.
If there are not enough distinct markers to secure a significant number of objects, PUFs’ encoding capability may be restricted. Owing to the unpredictability and huge parametric space provided by nanostructures paired with physiochemical procedures, this problem may be solved if PUFs are created using methods based on nanotechnology that provide a significant encoding potential which translates to a large quantity of distinct markers.
Critical Aspects of PUFs
The distinguishing physical trait is often a randomized two-dimensional or three-dimensional pattern, leading to various visual readings. Certain nanotechnology-based PUFs, like glass microbead randomized speckle patterning, inkjet-printed unclonable quantum dot (QD) fluorescent tags, and Au nanoparticle (NP) or Ag nanowire (NW) randomized patterns have lately been described.
Tag reading is crucial because several approaches depend on intricate hardware for verification, like dark-field, fluorescent, or electron microscopy, limiting their applicability for the overall supply chain needs, like mobility, quickness, repeatability, and reduced price of the procedure.
Salient Features of the Study
The technique suggested in this study aimed to achieve all of the aforementioned desirable characteristics, delivering an adequate anti-counterfeit approach via a rapid (1 minute), reversible, and equipment-free colorimetry reading facilitated by nanoscale Pt catalysts, which would be usable at any juncture of the supply network, even the end user.
Owing to the creation of a dependable AI method for quick and reliable visual marker authentication on the basis of Deep Learning and Computer Vision approaches, this nanotechnology-facilitated system may be readily encoded and then authorized via a cellphone.
Key Takeaways
In this study, the team demonstrated the possibility of merging chemistry, nanotechnology, and artificial intelligence to build novel cross-discipline techniques aimed at addressing critical sustainability and security challenges.
A sophisticated reversible PUF marker was presented that combined the achievement of distinct patterning with substantial encryption capabilities with a visual colorimetry reading perceptible by the human eye and analyzable using a cellphone.
The approach adopted by the team provided great ease in authenticating (i.e., equipment-free visual reading) as well as cutting-edge encryption capabilities by using the catalytic characteristics of nanoparticles. The suggested technique may be improved by creating various stochastic patterns and platforms, resulting in even greater security levels.
The ability to achieve repeated verification cycles in ambient settings, owing to the rapid (ON/OFF) color emergence/fading system evoked by the nanoscale platinum catalysts, opens up fresh avenues for in-situ analyses of potential counterfeits of high-quality goods throughout the entire supply network, from quality control after production to individual evaluation by the end-user.
News
Fever-Proof Bird Flu Variant Could Fuel the Next Pandemic
Bird flu viruses present a significant risk to humans because they can continue replicating at temperatures higher than a typical fever. Fever is one of the body’s main tools for slowing or stopping viral [...]
What could the future of nanoscience look like?
Society has a lot to thank for nanoscience. From improved health monitoring to reducing the size of electronics, scientists’ ability to delve deeper and better understand chemistry at the nanoscale has opened up numerous [...]
Scientists Melt Cancer’s Hidden “Power Hubs” and Stop Tumor Growth
Researchers discovered that in a rare kidney cancer, RNA builds droplet-like hubs that act as growth control centers inside tumor cells. By engineering a molecular switch to dissolve these hubs, they were able to halt cancer [...]
Platelet-inspired nanoparticles could improve treatment of inflammatory diseases
Scientists have developed platelet-inspired nanoparticles that deliver anti-inflammatory drugs directly to brain-computer interface implants, doubling their effectiveness. Scientists have found a way to improve the performance of brain-computer interface (BCI) electrodes by delivering anti-inflammatory drugs directly [...]
After 150 years, a new chapter in cancer therapy is finally beginning
For decades, researchers have been looking for ways to destroy cancer cells in a targeted manner without further weakening the body. But for many patients whose immune system is severely impaired by chemotherapy or radiation, [...]
Older chemical libraries show promise for fighting resistant strains of COVID-19 virus
SARS‑CoV‑2, the virus that causes COVID-19, continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid. Now, University of California San Diego scientists and an international team of [...]
Lower doses of immunotherapy for skin cancer give better results, study suggests
According to a new study, lower doses of approved immunotherapy for malignant melanoma can give better results against tumors, while reducing side effects. This is reported by researchers at Karolinska Institutet in the Journal of the National [...]
Researchers highlight five pathways through which microplastics can harm the brain
Microplastics could be fueling neurodegenerative diseases like Alzheimer's and Parkinson's, with a new study highlighting five ways microplastics can trigger inflammation and damage in the brain. More than 57 million people live with dementia, [...]
Tiny Metal Nanodots Obliterate Cancer Cells While Largely Sparing Healthy Tissue
Scientists have developed tiny metal-oxide particles that push cancer cells past their stress limits while sparing healthy tissue. An international team led by RMIT University has developed tiny particles called nanodots, crafted from a metallic compound, [...]
Gold Nanoclusters Could Supercharge Quantum Computers
Researchers found that gold “super atoms” can behave like the atoms in top-tier quantum systems—only far easier to scale. These tiny clusters can be customized at the molecular level, offering a powerful, tunable foundation [...]
A single shot of HPV vaccine may be enough to fight cervical cancer, study finds
WASHINGTON -- A single HPV vaccination appears just as effective as two doses at preventing the viral infection that causes cervical cancer, researchers reported Wednesday. HPV, or human papillomavirus, is very common and spread [...]
New technique overcomes technological barrier in 3D brain imaging
Scientists at the Swiss Light Source SLS have succeeded in mapping a piece of brain tissue in 3D at unprecedented resolution using X-rays, non-destructively. The breakthrough overcomes a long-standing technological barrier that had limited [...]
Scientists Uncover Hidden Blood Pattern in Long COVID
Researchers found persistent microclot and NET structures in Long COVID blood that may explain long-lasting symptoms. Researchers examining Long COVID have identified a structural connection between circulating microclots and neutrophil extracellular traps (NETs). The [...]
This Cellular Trick Helps Cancer Spread, but Could Also Stop It
Groups of normal cbiells can sense far into their surroundings, helping explain cancer cell migration. Understanding this ability could lead to new ways to limit tumor spread. The tale of the princess and the [...]
New mRNA therapy targets drug-resistant pneumonia
Bacteria that multiply on surfaces are a major headache in health care when they gain a foothold on, for example, implants or in catheters. Researchers at Chalmers University of Technology in Sweden have found [...]
Current Heart Health Guidelines Are Failing To Catch a Deadly Genetic Killer
New research reveals that standard screening misses most people with a common inherited cholesterol disorder. A Mayo Clinic study reports that current genetic screening guidelines overlook most people who have familial hypercholesterolemia, an inherited disorder that [...]















