Like our eyes, microscopes are limited in what they can see because of their resolution, or their ability to see detail. The detail, or information, from the object is there, but some of it gets lost as the light reflecting off of the object moves through the air.
“The whole premise of this is built on one single fact—the way light interacts with any matter is linear,” said Kamilov, assistant professor of electrical & systems engineering and computer science & engineering. “But the reality is that the interaction is actually not linear.”
For example, if you shine a flashlight through your hand, you can’t see the source of the light because it’s bending, and that is nonlinearity. With a single cell, the bending is so light that it is nearly transparent, which is linear.
When light interacts with a cell or an object, the light going out of the cell loses the information it gathers from that interaction. But because of that interaction, there are fluctuations in the vicinity of that cell that work with such matter and get retransformed and remitted. Those fluctuations are encoded into the nonlinearity of the interaction, but today’s microscopes are unable see this, Kamilov said.
“We want to take into account this nonlinear interaction of light, objects and premises, and if we do it correctly, we can extract that information, which normally disappears in a current microscope and is treated as ‘noise,'” Kamilov said. “We want to decode the information from the noise and add it back into the resolution, and that should give us features that are smaller than the resolution limit.”
Kamilov said there are two types of noise: imperfections and mathematical noise that is the result of science’s current limitations. It is the mathematical noise that he wants to capture.
![](https://www.nanoappsmedical.com/wp-content/uploads/2017/05/spacer.jpg)
Image Credit: Washington University in St. Louis
News This Week
Breakthrough in Antimicrobial Technology with Cinnamon-Based Nanokiller
The need for innovative antimicrobial agents has become increasingly urgent due to the rise of antibiotic-resistant pathogens and the persistent threat of infections acquired during hospital stays. Traditional antibiotics and antiseptics are often ineffective [...]
The Silent Battle Within: How Your Organs Choose Between Mom and Dad’s Genes
Research reveals that selective expression of maternal or paternal X chromosomes varies by organ, driven by cellular competition. A new study published today (July 26) in Nature Genetics by the Lymphoid Development Group at the MRC [...]
Study identifies genes increasing risk of severe COVID-19
Whether or not a person becomes seriously ill with COVID-19 depends, among other things, on genetic factors. With this in mind, researchers from the University Hospital Bonn (UKB) and the University of Bonn, in [...]
Small regions of the brain can take micro-naps while the rest of the brain is awake and vice versa
Sleep and wake: They're totally distinct states of being that define the boundaries of our daily lives. For years, scientists have measured the difference between these instinctual brain processes by observing brain waves, with [...]
Redefining Consciousness: Small Regions of the Brain Can Take Micro-Naps While the Rest of the Brain Is Awake
The study broadly reveals how fast brain waves, previously overlooked, establish fundamental patterns of sleep and wakefulness. Scientists have developed a new method to analyze sleep and wake states by detecting ultra-fast neuronal activity [...]
AI Reveals Health Secrets Through Facial Temperature Mapping
Researchers have found that different facial temperatures correlate with chronic illnesses like diabetes and high blood pressure, and these can be detected using AI with thermal cameras. They highlight the potential of this technology [...]
Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice
In a recent study published in the journal Nature, a team of researchers used murine models and various pharmacological and genetic approaches to examine whether pro-inflammatory signaling involving interleukin (IL)-11, which activates signaling molecules such [...]
Promise for a universal influenza vaccine: Scientists validate theory using 1918 flu virus
New research led by Oregon Health & Science University reveals a promising approach to developing a universal influenza vaccine—a so-called "one and done" vaccine that confers lifetime immunity against an evolving virus. The study, [...]
Leave A Comment