When a drug enters the body, it doesn’t generally target a particular part of the body. Paracetamol, for example, affects the whole body but its effects are felt at the source of pain. Likewise, cancer drugs can be imprecise; some enter the bloodstream to treat cancer at various anatomical points in the body, some are [...]
UNSW Sydney scientists have developed a way to control the shape of polymer molecules so they self-assemble into non-spherical nanoparticles - an advance that could improve the delivery of toxic drugs to tumours. "Very little in nature is perfectly spherical," says study senior author Professor Pall Thordarson of the UNSW School of Chemistry. "Most biological [...]
From the abstract: Isocitrate dehydrogenases play important roles in cellular metabolism and cancer. This review will discuss how the roles of isoforms 1 and 2 in normal cell and cancer metabolism are distinct from those of isoform 3. It will also explain why, unlike 1 and 2, mutations in isoform 3 in tumor are not likely [...]
The company GB Sciences Inc. has obtained the exclusive global worldwide intellectual property license for this innovative solution, which is based on nanotechnology. The researchers Lucía Martín Banderas and Mercedes Fernández Arévalo, from the I+DNanomed research group at the University of Seville, have patented an innovative formulation based on nanotechnology, which is designed to relieve [...]
Leiden and Jülich researchers discovered an elegant and simple approach to improve the sensitivity of graphene biosensors. These so-called 'next generation graphene electronic biochemical sensor devices' are able to detect very low amounts of HIV DNA thanks to their very low electronic noise. The richness of electronic properties of graphene has attracted enormous interest for [...]
Silver nanoparticles (AgNPs) are known to have excellent antibacterial properties and are considered by many to be a strong contender in the critical search for an answer to antibiotic-resistant bacteria. They block enzymes and can cause bacteria to have irregularly shaped membranes, producing results ranging from inhibited growth to cell death. However, a collaboration of [...]
The nanomedicines market is worth billions and, despite a variety of hurdles, it continues to attract the attention of venture capitalists. Tarun Pandotra reviews developments in the sector. Nanotechnology has come a long way in the last five years and now nanomedicine, a marriage of nanotechnology and medicine, is taking its place in the fight [...]
Root canal treatment may soon be more effective because of a miniature but powerful ally that could inhibit infection after treatment. A team of Researchers at the UCLA School of Dentistry and the UCLA Henry Samueli School of Engineering and Applied Science discovered in a clinical trial that nanodiamonds protected disinfected root canals after the [...]
University of Surrey scientists have developed ‘intelligent’ nanoparticles capable of heating up to a temperature that is high enough to kill cancerous cells – but which can self-regulate and lose heat before they get hot enough to harm healthy tissue. It may be possible to use the self-stopping nanoparticles very soon as part of hyperthermic-thermotherapy [...]
Researchers at Chalmers University of Technology and the Technical University of Denmark have developed a method that makes it possible to map the individual responses of nanoparticles in different situations and contexts. The results pave the way for better nanomaterials and safer nanotechnology and were recently published in the journal Nature Communications. In the future [...]
