Autoimmune diseases are widespread and notoriously difficult to treat. In part, this is because why the immune system attacks its own tissues in patients with these conditions remains poorly understood. In a study recently published in Cell, researchers from Osaka University have revealed that the body's own proteins with unusual structure trigger immune cells to [...]
In a recent study published in the journal PLOS ONE, researchers conducted a systematic review and meta-analyzed data on the impact of coronavirus disease 2019 (COVID-19) on male reproductive hormones and semen variables to determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections had an adverse impact on male fertility. Background The etiological agent [...]
New method uses patient-derived neurons to effectively simulate late-onset Alzheimer’s and identify possible treatments. Researchers at Washington University School of Medicine in St. Louis have created a technique to explore the impact of aging on Alzheimer’s disease development. This new method allows for the study of aged neurons in the laboratory without requiring a brain biopsy, which could [...]
Teenage girls' brains may have prematurely aged by up to four years during the Covid pandemic, an American study suggests. Adolescent boys weren't immune either with their brain's also showing signs of undue wear and tear, albeit by only one-and-a-half years. Experts suggested the difference was due to lockdown's social restrictions having a disproportionate impact [...]
Routine lab tests are not reliable for diagnosing Long COVID, according to a new study. The research found that no clinical lab values could serve as biomarkers, highlighting the need to focus on symptoms for diagnosis. A new study found that most routine laboratory tests are not reliable for diagnosing Long COVID, also known [...]
Researchers have created nanoscale robots which could be used to manage bleeds in the brain caused by aneurysms. The development could enable precise, relatively low-risk treatment of brain aneurysms, which cause around 500,000 deaths globally each year. The medical condition—a blood-filled bulge on a brain artery that can rupture and cause fatal bleeds—can also lead [...]
Anita Saraf investigates mosquito saliva to understand how viruses like dengue and West Nile are transmitted, using mass spectrometry to identify potential targets for vaccines and treatments. You might guess it’d be tough to extract saliva from a mosquito. And you’d be correct. Yet, because mosquitos spread disease via saliva, it’s critical to sample [...]
Nanomedicine, a branch of nanotechnology, is revolutionizing healthcare by enabling the manipulation of materials at the nanoscale to diagnose, treat, and prevent diseases. Unlike traditional treatments, nanoparticles (NPs) are highly precise in targeting diseased cells at the molecular level, enhancing the effectiveness of treatments for conditions like cancer, diabetes, infectious diseases, chronic pain, and [...]
As the global threat of H5N1 influenza looms with outbreaks across species and continents including the U.S., three international vaccine and public health experts say it is time to fully resource and support a robust strategy to address this and future potential pandemic influenza threats, including to consider voluntary vaccination for those now at [...]
In a recent study published in Nature Immunology, a team of researchers from the United States used non-human primate models to compare the protection conferred by an intramuscular booster dose of the bivalent messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccine with that provided by a booster dose of a mucosal bivalent adenoviral vector vaccine delivered [...]
