Scientists at the University of Michigan Rogel Cancer Center were optimistic when they identified a small molecule that blocked a key pathway in brain tumors. But there was a problem: How to get the inhibitor through the bloodstream and into the brain to reach the tumor. In collaboration with multiple labs, the teams fabricated [...]
According to scientists at Georgia State University’s Institute for Biomedical Sciences, a nanoparticle vaccine that incorporates two proteins that stimulate immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that prompted the disease outbreak, has the potential for broader, safer SARS-CoV-2 vaccines. Since 2019, the SARS-CoV-2 epidemic has caused more than six [...]
Post-viral infection sequelae have included neurological syndromes. Among these is the association of parkinsonian manifestations with a prior history of viral infection, as far back as the Spanish flu pandemic of 1918, when encephalitis lethargica was recognized as a long-term complication of the flu. A new paper examines the possibility of similar syndromes following [...]
They call them long-haulers – people still suffering symptoms long after a bout of COVID. But what is the condition, exactly? Doctors expect the answer will change our understanding of immunity forever. Six months after physiotherapist Scott Willis became one of Australia’s first COVID-19 patients, something strange [...]
Microbubbles can assist with localized drug delivery in a patient's body by popping at a target site to create enhanced permeability of tumor blood vessels. By temporarily increasing the porosity of the blood vessels, the microbubbles can create a means for coinjected anti-cancer drugs to preferentially leak into the tumor for treatment. Naomi Matsuura, [...]
In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers at Linköping University (LiU), Sweden, have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid. The discovery of [...]
Glucose is the sugar we absorb from the foods we eat. It is the fuel that powers every cell in our bodies. Could glucose also power tomorrow’s medical implants? Engineers at MIT and the Technical University of Munich think so. They have designed a new kind of glucose fuel cell that converts glucose directly [...]
Although skin aging has not been related to many health complications, it has aesthetic issues. Some of the common symptoms of skin aging are changes in the skin texture (rough, dry, and itchy), discoloration, reduction in skin elasticity, and enhanced susceptibility to bruises. Scientists have formulated various nano-based products to reverse, prevent or decelerate [...]
In an article published in the journal Science of the Total Environment, researchers have highlighted the significance and potential risks associated with the release of nanoparticles from coal-fired power plants. Applying the single-particle inductively coupled plasma mass technique, the particle size and particle number concentration (PNC) of conventional metal-containing nanoparticles (Fe and Ti containing nanoparticles) were investigated. [...]
A paper recently published in the journal ACS Applied Energy Materials demonstrated the feasibility of using a covalent organic framework (COF)-based nanofluidic hybrid membranes (NHMs) to attain enhanced interfacial ion transport for the generation of osmotic energy. Importance of Osmotic Energy Osmotic energy exists in the form of a salinity gradient between seawater and freshwater and [...]
