For a third season, COVID-19 cases are rising ahead of the holidays, this time with a more recent variant driving infections.
Cases of JN. 1 infections rose from just more than 8% at the end of November to double digits by Dec. 9, according to CDC data.
International health experts say the sudden jump isn’t cause for concern—yet.
Here’s what you need to know:
What is JN.1?
The JN.1 variant is closely related to another omicron subvariant named BA.2.86, according to the CDC.
Health officials started tracking BA.2.86 in August but noticed some cases had a single change to the spike protein, the part of a virus that penetrates host cells to cause infection, according to the CDC.
JN.1 was first detected as its own variant in the United States in September, the CDC reported, and has since been identified in 11 countries.
The variant made up just 0.1% of cases at the end of October, according to CDC data, but that number has now increased exponentially.
“The continued growth of JN.1 suggests that it is either more transmissible or better at evading our immune systems,” the CDC said at the beginning of December.
This means the change to the spike protein may make it easier for the virus to get into cells than previous variants or make it harder for human immune systems to identify the virus as COVID-19.
International health experts also noted the trend, with JN.1 officially classified as its own variant by the World Health Organization on Dec. 19.
“Based on the available evidence, the additional global public health risk posed by JN.1 is currently evaluated as low,” the WHO said in a post on X, formerly known as Twitter. “Despite this, with the onset of winter in the Northern Hemisphere, JN.1 could increase the burden of respiratory infections in many countries.”
Does the updated COVID booster protect against JN.1?
The CDC says the JN.1 variant is closely related enough to previous variants that the updated COVID-19 booster shot will provide protection.
“The spike protein—called a ‘spike’ because it looks like tiny spikes on the virus’ surface—plays a crucial role in helping the virus infect people. Because of this, the spike protein is also the part of the virus that vaccines target, meaning vaccines should work against JN.1 and BA.2.86 similarly,” the CDC said.
The agency continued by saying it expects “treatments and testing to remain effective” against JN.1, in line with previous variants.
The most recent COVID-19 booster was approved by the Food and Drug Administration and then recommended by the CDC in September, but a large number of Americans have opted out of the shot.
Do I need the new COVID booster?
The vaccine is recommended for everyone over the age of six months, regardless of previous vaccine status, the CDC says.
Despite this, fewer and fewer Americans are adding the shot to their regular seasonal vaccines, like the flu shot.
By the middle of November, only 36 million adults and 3.5 million children had received the latest shot, equivalent to about 14% of the American public, ABC News reported.
That’s compared to the nearly 70% of Americans who completed the primary series of COVID-19 vaccines, McClatchy News reported.
Cases of JN.1 have seen some of the highest increases in Midwestern states, CDC data shows, correlating with a pocket of the U.S. that has been particularly hesitant to get the new shot.
Ahead of the holidays, the CDC reiterated the vaccine, masking and keeping your distance when you might be sick are still the most effective ways to prevent a COVID-19 infection and prevent its spread.
The agency said this also extends to other respiratory illnesses making the rounds this season.
“Many viruses spread more during the holiday season, so it is important to get all recommended vaccines, including flu, COVID-19 and RSV, as soon as possible,” the CDC said. “This will give you the best protection against these respiratory diseases, including while traveling and gathering with family and friends. These vaccines will also make your illness less severe if you do get sick.”
News
Ebola control is weakened by mistrust and cultural insensitivity
Effective response depends on cooperation with communities and frontline workers, writes Zaeem ul Haq The current Bundibugyo Ebola outbreak in the Democratic Republic of the Congo (DRC) and Uganda is exposing dangerous gaps in [...]
Building the Brain Requires Millions of Dangerous DNA Breaks
Scientists discovered that building a healthy brain involves an unexpected step: young neurons routinely break and rapidly repair their own DNA. As the brain develops, newly formed nerve cells must travel through tightly packed tissue [...]
One Tiny Change May Explain How Viruses Jump From Bats to Humans
Scientists found that one tiny genetic change may determine whether a bat virus stays in bats or becomes a human threat. Most infectious disease outbreaks begin when a virus or other pathogen crosses from animals into [...]
Scientists Discover 250+ Genes That Could Lead to New Ways To Prevent Melanoma
The world’s largest study of mole genetics identified hundreds of genes tied to melanoma risk, uncovering potential new drug targets and paving the way for more accurate melanoma screening and prevention. Researchers at QIMR [...]
Breakthrough Diabetes Treatment Reprograms the Immune System
An engineered stem cell therapy reversed new-onset Type 1 diabetes in mice by shifting the immune system away from attacking insulin-producing cells. For more than a century, people with Type 1 diabetes have relied [...]
Taking the world’s temperature: WHO chief spotlights global health emergencies
Taking the world’s temperature on pressing health matters, WHO Director-General Tedros Adhanom Ghebreyesus provided the latest on current global challenges - and successes when it comes to international cooperation. “The outbreaks of hantavirus, Ebola and Marburg all show [...]
Scientists Create Tiny “Mini Livers” That Could One Day Replace Liver Transplants
Engineered tissue grafts could help perform key liver functions and benefit thousands of people living with liver failure. The liver is one of the body’s hardest-working organs, carrying out hundreds of vital jobs, from [...]
NanoMedical Brain/Cloud Interface – Explorations and Implications. A new book from Frank Boehm
New book from Frank Boehm, NanoappsMedical Inc Founder: This book explores the future hypothetical possibility that the cerebral cortex of the human brain might be seamlessly, safely, and securely connected with the Cloud via [...]
Scientists Discover Surprising Way To Help the Brain Recover After Stroke
A new study suggests that strengthening the body’s natural circadian rhythms may help the brain recover after stroke, even when treatment begins days after the injury. Every year, millions of people survive a stroke, [...]
Our books now available worldwide!
Online Sellers other than Amazon, Routledge, and IOPP Indigo Global Health Care Equivalency in the Age of Nanotechnology, Nanomedicine and Artifcial Intelligence Global Health Care Equivalency In The Age Of Nanotechnology, Nanomedicine And Artificial [...]
Younger Generations Are Aging Faster – and It May Be Fueling a Surge in Cancer
Younger generations may be aging biologically faster than those before them, and that shift could help explain rising rates of cancer at younger ages. For decades, cancer was viewed largely as a disease of [...]
Using Cannabis Could Raise Your Stroke Risk by 37%, Massive Study Reveals
Large-scale evidence suggests cannabis, cocaine, and amphetamines may directly raise stroke risk, including in younger adults. As recreational drug use becomes increasingly common, researchers are uncovering evidence that its health consequences may extend far beyond [...]
Could Vitamin C Be the Secret to Keeping Your Brain Younger?
Lower vitamin C levels were linked to reduced brain volume and weaker neural connectivity in older adults, suggesting a potential connection between nutrition and brain health. Could a common vitamin help preserve the brain [...]
This Deadly Disease Was Wiping Out Humans 5,500 Years Ago
A new study suggests plague was already a deadly threat 5,500 years ago, striking small hunter-gatherer communities long before cities and agriculture emerged. For centuries, plague has been remembered as the disease that devastated [...]
China closing in but US leads in biotech quality, commercial reach, survey finds
SAN DIEGO, June 22 (Reuters) - China, which now conducts more clinical drug trials, opens new tab than the U.S., still lags in the quality and commercial reach of its biomedical science, according to a recent survey, opens new [...]
New method generates renewable supply of progenitor immune cells
In a paper published in Cell, a USC Stem Cell-led team reports a new way of generating a renewable and expandable supply of the progenitor cells that give rise to macrophages. These immune cells help [...]















