Antibodies are remarkable biomarkers: they are the cues that provide us with indications about many diseases and how our immune system counter them. Now a group of scientists from the University of Rome, Tor Vergata (Italy) has found a way to repurpose them so that they can trigger a specific chemical reaction. "We demonstrated a [...]
Using post-mortem tissue samples, a team of researchers from Charité – Universitätsmedizin Berlin have studied the mechanisms by which the novel coronavirus can reach the brains of patients with COVID-19, and how the immune system responds to the virus once it does. The results, which show that SARS-CoV-2 enters the brain via nerve cells in [...]
Scientists used human white blood cell membranes to carry two drugs, an antibiotic and an anti-inflammatory, directly to infected lungs in mice. The nano-sized drug delivery method developed at Washington State University successfully treated both the bacterial growth and inflammation in the mice's lungs. The study, recently published in Communications Biology, shows a potential new [...]
The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a study led by UCL researchers in the i-sense McKendry group. Paper-based lateral flow tests work the same way as a pregnancy test in that a [...]
WEHI researchers are studying 'nanobodies' – tiny immune proteins made by alpacas—in a bid to understand whether they might be effective in blocking SARS-CoV-2, the virus that causes COVID-19. Alpacas produce unique antibodies—called nanobodies—that can bind very specifically to a protein. The research team are developing nanobodies specific for the SARS-CoV-2 'spike' protein, which sticks [...]
The University of Oxford, in collaboration with AstraZeneca plc, today announces interim trial data from its Phase III trials that show its candidate vaccine, ChAdOx1 nCoV-2019, is effective at preventing COVID-19 (SARS-CoV-2) and offers a high level of protection. Our vaccine work is progressing quickly. To ensure you have the latest information or to find [...]
A genetic modification in the ‘coat’ of a brain infection-causing virus may allow it to escape antibodies, according to Penn State College of Medicine researchers. They say testing people for this and other viral mutations may help identify patients at risk for developing a fatal brain disease. Dr. Aron Lukacher, professor and chair of the [...]
Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells. Now, researchers reporting in ACS' Nano Letters have designed DNA-based nanogels that only break down and release their chemotherapeutic contents within cancer cells, minimizing the impacts on normal ones and potentially eliminating painful and uncomfortable side [...]
The new technology behind Pfizer's and Moderna's coronavirus vaccines could be used to prevent everything from heart disease to cancer, experts say. The breakthrough vaccine 'platform' they use transforms the body into a virus-zapping vaccine factory and could be retooled to run interference on other diseases and speed the development of shots to prevent future [...]
Current state-of-the-art techniques have clear limitations when it comes to imaging the smallest nanoparticles, making it difficult for researchers to study viruses and other structures at the molecular level. Scientists from the University of Houston and the University of Texas M.D. Anderson Cancer Center have reported in Nature Communications a new optical imaging technology for [...]
