Novel drugs, such as vaccines against covid-19, among others, are based on drug transport using nanoparticles. Whether this drug transport is negatively influenced by an accumulation of blood proteins on the nanoparticle’s surface was not clarified for a long time. Scientists at the Max Planck Institute for Polymer Research have now followed the path [...]
Imagine it is 2030. Doctors in a regional hospital in country X note an expanding cluster of individuals with severe respiratory disease. Rapid whole-genome sequencing identifies the disease-causing agent as a novel coronavirus. Epidemiological investigations suggest the virus is highly infectious, with most initial cases requiring hospitalisation. The episode bears a striking resemblance to [...]
A predictive model has been developed that enables researchers to encode instructions for cells to execute. Scientists at the University of California, San Francisco (UCSF) and IBM Research have created a virtual library of thousands of “command sentences” for cells using machine learning. These “sentences” are based on combinations of “words” that direct engineered immune cells to find [...]
It's "lights out" for antibiotic-resistant superbugs as next-generation light-activated nanotech proves it can eradicate some of the most notorious and potentially deadly bacteria in the world. Developed by the University of South Australia and published in Pharmaceutics, the new light therapy can eliminate antibiotic-resistant superbugs golden staph and Pseudomonas aeruginosa by 500,000-fold and 100,000-fold [...]
Nanoparticles are complex materials smaller than 100 nanometers, or about the size of a virus, but they have a large range of potential applications, from medicine to energy to electronics. Now, hundreds of new nanoparticles with previously unknown features have been produced using an innovative experimental approach. Chemists usually make materials by finding the [...]
A novel combination of artificial intelligence and production techniques could change the future of nanomedicine, according to Cornell researchers using a new $3 million grant from the National Science Foundation to revolutionize how polymer nanoparticles are manufactured. Polymer nanoparticles have emerged as a powerful tool for delivering medicine to precisely the right place, at [...]
Trauma can have a profound impact on an individual’s life. Recent research has shed light on how traumatic events can alter the physical structure of our brains. These changes are not due to physical injury but rather the brain’s ability to adapt and rewire itself after these experiences. The ZVR Lab at the Del [...]
Biorealistic organic electrochemical neurons enabled by ion-tunable antiambipolarity in mixed ion-electron conducting polymers. Work to develop increasingly functional artificial nerve cells continues at the Laboratory for Organic Electronics, LOE. In 2022, a team of scientists led by associate professor Simone Fabiano demonstrated how an artificial organic neuron could be integrated into a living carnivorous [...]
Stress-induced retinal aging produces symptoms similar to those that occur naturally with aging. New research from the University of California, Irvine, indicates that aging plays a significant role in the death of retinal ganglion cells in glaucoma and that new treatment methods for glaucoma patients can target these unique pathways. The study was published in Aging [...]
Altering a cellular process can lead stem cells—cells from which other cells in the body develop—to die or regenerate, according to a new study led by Cedars-Sinai and the University of California, San Francisco (UCSF). The findings, to be published today (January 13) in the peer-reviewed journal Cell Stem Cell, may assist in the development of new drugs that [...]
