A team of researchers working at China’s Fourth Hospital of Harbin Medical University has developed a new kind of male contraceptive that is easily reversed. In their paper published in the journal ACS Nano, the group describes their approach, the elements that went into making their contraceptive and how well it worked when tested on rats.
The hydrogel has already been approved for use in the body for other purposes, and has been deemed safe. The researchers added thioketals to the gel, which prior research has shown become disassociated when exposed to molecules containing oxygen. They also added a small amount of titanium dioxide, which releases oxygen when blasted with ultrasound. In practice, the hydrogel is injected into the vas deferens, which are the tubes that carry sperm from the testicles to the penis during ejaculation. Blocking them blocks the sperm, preventing them from being mixed with semen, and thus preventing the ability of the patient to impregnate a woman. Removing the hydrogel is done by blasting the area with a small amount of ultrasound. This releases the oxygen in the titanium dioxide, which in turn breaks down the gel, allowing it to be washed out via the penis.
The researchers tested their hydrogel with male lab rats. Some were given the hydrogel; others got a vasectomy, and others yet got saline. After they healed, the rats were allowed to mate with females. Only those that were given the saline produced offspring. The researchers also removed the gel from the test rats using an ordinary ultrasound device and found that it fully restored their ability to reproduce. More testing is required to ensure its safety before trials can begin in humans.
In an article published in the journal Science of the Total Environment, researchers have highlighted the significance and potential risks associated with the release of nanoparticles from coal-fired power plants. Applying the single-particle inductively coupled plasma mass [...]
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A paper recently published in the journal Nature Communications demonstrated an effective method to realize on-chip nanophotonic topological rainbow devices using the concept of synthetic dimensions. Importance of Synthetic Dimensions for the Construction of Topological Nanophotonics [...]
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Microrobots have the potential to revolutionize medicine. Researchers at the Max Planck ETH Centre for Learning Systems have now developed an imaging technique that for the first time recognises cell-sized microrobots individually and at [...]
Scientists have recently developed multifunctional hexagonal NaxWO3 nanocrystals that can serve as microwave sensitizers to kill cancer cells as well as improve the overall chemodynamic therapy (CDT). This study is available as a pre-proof in Chemical Engineering Journal. [...]
Apple’s visionary founder, the late Steve Jobs once said, “the biggest innovations of the 21st century will be at the intersection of biology and technology”. And that prediction is coming true in the drug [...]
Chemical separation processes are essential in the manufacturing of many products from gasoline to whiskey. Such processes are energetically costly, accounting for approximately 10–15 percent of global energy consumption. In particular, the use of [...]
Scientists have recently developed electrochemical immunosensors based on graphene oxide−gold (GO−Au) nanocomposites. These immunosensors are highly sensitive with dual function, i.e., they can detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen and antibody. [...]