Human trials of a potential coronavirus vaccine being developed by scientists in Oxford are reported to have shown promising results.
The researchers believe they have made a breakthrough after discovering the jab could provide “double protection” against the virus, the Daily Telegraph reported.
The newspaper said the phase 1 trial in healthy adult volunteers, which began in April, showed the vaccine generated an immune response, with blood samples indicating it stimulated the body to produce both antibodies and “killer T-cells”.
It came as Health Secretary Matt Hancock said teams were working towards a “best-case scenario” of a vaccine being made available some time this year, although he conceded it was more likely in 2021.
David Carpenter, chairman of the Berkshire Research Ethics Committee, which approved the Oxford trial and continues to work with scientists on amendments, told the Telegraph that the team were “absolutely on track”.
“They can strengthen findings by targeting people in hospitals, healthcare professionals, where the spread is [more] likely to happen,” he said.
“Nobody can put final dates… things might go wrong but the reality is that by working with a big pharma company, that vaccine could be fairly widely available around September and that is the sort of target they are working on.
But a source told the newspaper that the results did not yet prove that the Oxford vaccine, known as ChAdOx1 nCoV-19, provides long-lasting immunity.
“I can tell you that we now know the Oxford vaccine covers both bases – it produces both a T cell and an antibody response,” the source said.
“It’s the combination of these two that will hopefully keep people safe. So far, so good. It’s an important moment. But we still have a long way to go.”
Image Credit: Science Focus
Thanks to Heinz V. Hoenen. Follow him on twitter: @HeinzVHoenen
News This Week
Omicron subvariant BA.2 – which was dominant worldwide early this year, including in Hong Kong – replicates more swiftly than other strains and causes faster programmed cell death in human brains, a new study has found. [...]
The urgent need to remove excess carbon dioxide from Earth’s environment could include enlisting some of our planet’s smallest inhabitants, according to an international research team led by Michael Hochella of the Department of [...]
Blood pressure is a key vital sign that provides insight into our cardiovascular health. But blood pressure is typically measured only a few times per year by a clinician—and these measurements might not always [...]
A South African laboratory study using Covid-19 samples from an immunosupressed individual over six months showed that the virus evolved to become more pathogenic, indicating that a new variant could cause worse illness than [...]
For the past several months, Omicron subvariants BA.4 and BA.5 have dominated COVID-19 cases in the U.S. But now, there’s a class of new COVID subvariants on the rise and one in particular is getting plenty of [...]
Nucleic acid therapies involving DNA or RNA have significant potential to treat genetic disorders, infectious diseases, and cancer; however, research suggests that less than 1% of injected nucleic acid doses reach target cells in [...]
The US Food and Drug Administration on Tuesday approved Hemgenix, a new drug to treat hemophilia. Manufacturer CSL Behring set the price at $3.5 million per treatment, making it the most expensive drug [...]
Some wounds just won’t heal. Infections, diseases like diabetes, and suppressed immune systems often stack up to slow healing. Chronic wounds can last months and lead to anxiety and depression. In the worst cases, [...]
Over the years, researchers have tried hard to comprehend topographic signals that promote cell mechanical sensitive responses. The extracellular matrix (ECM) provides a complex cellular microenvironment that controls cellular behavior. Nevertheless, only a few [...]
There is now an imminent threat of measles spreading in various regions globally, as COVID-19 led to a steady decline in vaccination coverage and weakened surveillance of the disease, the World Health Organization (WHO) [...]
In a recent study, it was shown that people with long Covid have had physical changes to their brains several months after experiencing the initial infection. The study included MRIs of patients who continued [...]
Western University in London, Ont., is building a unique research lab to study humanity's greatest viral threats — a secret weapon, if you will, one that it's expected would put Canada and the world in a better position if [...]
Cancer patients are testing a medicine made of antibodies that were designed from scratch on a computer in Israel and whose inventor has “programmed” them to “decide” whether cells surrounding tumors are bad or good. [...]
In an article published in the journal Scientific Reports, researchers presented the potentiostatic deposition used to electrodeposit nickel (Ni) and nickel-graphene (Ni-G) films on copper substrates. Myristic acid (MA) was employed to alter the plane of the [...]
Oregon State University scientists have invented a way to make magnetic nanoparticles that get hotter than any previous nanoparticle, improving their cancer fighting ability. Faculty from the OSU College of Pharmacy spearheaded a collaboration [...]