A single nasal spray vaccine may one day protect against viruses, pneumonia, and even allergies. For decades, scientists have dreamed of creating a universal vaccine capable of protecting against many different pathogens. The idea has often been compared to a Holy Grail of medicine — a goal that seemed almost impossible to achieve. Now, [...]

Scientists have developed an AI system that analyzes complex gene-expression signatures to estimate the likelihood that a tumor will spread. Why do some tumors spread throughout the body while others remain confined to their original location? Scientists still do not fully understand the processes that determine whether cancer cells gain the ability to metastasize. [...]

In Lake Malawi, hundreds of species of cichlid fish have evolved with astonishing speed, offering scientists a rare opportunity to study how biodiversity arises. Researchers have identified segments of “flipped” DNA that may allow fish to adapt rapidly to new environments and eventually form new species. These unusual genetic changes appear to function as evolutionary “superchargers,” helping populations [...]

A new study provides the first direct biological evidence explaining why some people continue to experience taste loss long after recovering from COVID-19. Researchers have uncovered specific biological changes in taste buds that could help explain why a small number of people continue to struggle with taste loss long after a COVID-19 infection. The study, [...]

Catching Covid significantly raises the risk of developing deadly kidney disease, research has shown. The virus was found to increase the chances that patients will develop the incurable condition by around 50 per cent. Researchers at Penn State College of Medicine in the US, who carried out the study, are now calling for Covid [...]

Researchers have developed a targeted approach to combat periodontitis without disrupting the natural balance of the oral microbiome. The innovation could reshape how gum disease is treated while preserving beneficial bacteria. The human mouth contains a remarkably complex community of more than 700 bacterial species, yet only a small fraction are responsible for periodontitis. These [...]

The Kunming Montreal Global Biodiversity Framework calls for the elimination of plastic pollution by 2030. If that goal has been clearly set, why have meaningful measures that create real change still not been implemented? Plastic pollution is more than just trash on the beach. Marine plastic waste releases PFAS and heavy metals into the [...]

Researchers tested new CAR designs in NK-92 cells and found the modified cells killed tumor cells more effectively, showing stronger anti-cancer activity. Researchers at the Ribeirão Preto Blood Center and the Center for Cell-Based Therapy (CTC) are exploring a key question in cancer immunotherapy: how to “wire” engineered natural killer (NK) cells so they [...]

A new study from researchers highlights an unexpected player in Alzheimer’s disease: aging astrocytes. Senescent astrocytes have been identified as a major contributor to Alzheimer’s progression. The cells lose protective functions and fuel inflammation, particularly in APOE4 carriers. The findings highlight senolytic drugs as a potential new therapy. For the first time, the research team has [...]

Successful root canal treatment may help lower inflammation associated with heart disease and improve blood sugar and cholesterol levels. Treating an infected tooth with a successful root canal procedure may do more than relieve pain. New research suggests it could also lower inflammation tied to heart disease and improve blood sugar and cholesterol levels. [...]