A study in Scientific Reports evaluated a photoacoustic polydopamine-indocyanine green (PDA-ICG) nanoprobe for detecting senescent cells. Senescent cells play a role in tumor progression and therapeutic resistance, with potential adverse effects such as inflammation and tissue disruption. The PDA-ICG nanoprobe offers a method for identifying these cells, with implications for cancer diagnostics and treatment.   Background [...]

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, improper immune responses, or errors in development. These dysregulations are the basis for diseases like cancer, diabetes, and autoimmune disorders. What is cell signaling? Cell signaling [...]

Researchers at the Weizmann Institute have developed a biodegradable composite material that could play a significant role in addressing the global plastic waste crisis. Billions of tons of plastic waste clutter our planet. Most of it accumulates on land, settles in the oceans, or disintegrates into tiny particles called microplastics, which pollute the air [...]

New research from the Human Cell Atlas offers insights into cell development, disease mechanisms, and genetic influences, enhancing our understanding of human biology and health. The Human Cell Atlas (HCA) consortium has made significant progress in its mission to better understand the cells of the human body in health and disease, with a recent [...]

Researchers at the LOEWE Centre for Translational Biodiversity Genomics (TBG) have discovered a significant diversity of enzymes in spider venom, previously overshadowed by the focus on neurotoxins. These enzymes, found across 140 different families, could revolutionize industries by offering sustainable solutions in waste management and detergent manufacturing due to their biochemical properties. This discovery [...]

Precision medicine is reshaping healthcare by tailoring treatments to individual patients based on their unique genetic, environmental, and lifestyle factors. At the forefront of this revolution, the integration of quantum computing and machine learning (ML) promises to bring faster, more accurate, and highly personalized diagnostics and therapies. This article goes into some of the [...]

Menadione, a vitamin K precursor, shows promise in slowing prostate cancer in mice by disrupting cancer cell survival processes, with potential applications for human treatment and myotubular myopathy therapy. Prostate cancer is a quiet killer. In most men, it’s treatable. While it’s treatable in many men, some cases prove resistant to all current therapies [...]

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it into protein. But this step has been a visual mystery; scientists previously did not know how the ribosome attaches to [...]

Smoking and vaping impair vascular function, even without nicotine, with the most significant effects seen in nicotine-containing e-cigarettes. Researchers recommend avoiding both for better health. Researchers have discovered immediate impacts of cigarette and e-cigarette smoking on vascular function, even in the absence of nicotine. Findings from the ongoing study were recently presented at the [...]

Twice-yearly injections of the capsid inhibitor drug lenacapavir can prevent the vast majority of HIV infections, according to a Phase 3 clinical trial published Wednesday in the New England Journal of Medicine. HIV pre-exposure prophylaxis (PrEP) has emerged as a crucial tool for fighting the global HIV epidemic, but researchers say daily pill regimens [...]