Seeing RNA at the nanoscale (with video)

 

Cells contain thousands of messenger RNA molecules, which carry copies of DNA’s genetic instructions to the rest of the cell. MIT engineers have now developed a way to visualize these molecules in higher resolution than previously possible in intact tissues, allowing researchers to precisely map the location of RNA throughout cells.

Key to the new technique is expanding the tissue before imaging it. By making the sample physically larger, it can be imaged with very high resolution using ordinary microscopes commonly found in research labs.

“Now we can image RNA with great spatial precision, thanks to the expansion process, and we also can do it more easily in large intact tissues,” says Ed Boyden, an associate professor of biological engineering and brain and cognitive sciences at MIT, a member of MIT’s Media Lab and McGovern Institute for Brain Research, and the senior author of a paper describing the technique in the July 4, 2016 issue of Nature Methods (“Nanoscale imaging of RNA with expansion microscopy”).

 

Read more

 

 

Image credit: Yosuke Bando, Fei Chen, Dawen Cai, Ed Boyden, and Young Gyu

 

Recent News

The Theranos deception

Elizabeth Holmes was just 19 years old when she dropped out of Stanford University with a dream of creating a company that would revolutionize blood testing. As we first reported last May, Holmes founded [...]

LAUNCH.nano: MIT.nano Grand Opening celebration, Oct. 4, 2018

After six years of design and construction, MIT.nano will celebrate the completion of the facility at a Grand Opening Event on Oct. 4. Please join us for a day of activities including a symposium [...]

Scientists Use Light to Control Nanobots

If nanotechnology has one clear image in the collective pop-culture consciousness, it is that of nanorobots, nanoscale machines capable of performing mechanical functions. When considering the potential of such a technology, the more astute may [...]

10 Steps to Adopting Artificial Intelligence in Your Business

Artificial intelligence (AI) is clearly a growing force in the technology industry. Chatbots and virtual assistants are becoming a key part of new products, and robots are taking center stage at conferences and showing [...]

Arguing the Pros and Cons of Artificial Intelligence in Healthcare

In what seems like the blink of an eye, mentions of artificial intelligence have become ubiquitous in the healthcare industry. From deep learning algorithms that can read CT scans faster than humans to natural [...]

International Conference On Nanomedicine And Nanobiotechnology – ICONAN Rome 2018

The International Conference On Nanomedicine And Nanobiotechnology is an annual event. It hosts high-profile plenary speakers, world-class researchers, oral and poster presentations, workshops, sponsor exhibits and afterworks. It is a great opportunity to share [...]

Australian Scientists Develop Nanotechnology To Purify Water

SYDNEY, (UrduPoint / Pakistan Point News, app - 14th Sep, 2018 ) :Scientists in Australia have developed a ground-breaking new way to strip impurities from waste water, with the research set to have massive [...]

A new scientific field: Quantum metamaterials

Two teams of scientists from the Technion-Israel Institute of Technology have collaborated to conduct groundbreaking research leading to the development of a new and innovative scientific field: Quantum Metamaterials. The findings are presented [...]

Using biosensors to deliver personalized doses of antibiotics

A team of eight EPFL students has come up with a portable biosensor that can measure the amount of vancomycin in a patient's blood stream, enabling doctors to better control the dosage and reduce [...]

Transparent high-resolution EEG array allows brain imaging

Researchers have developed a see-through, dual-layered, mesh EEG device which is capable of measuring the electrical activity of individual neurons… Researchers from Boston Children’s Hospital and Northeastern University developed a ‘see-through’ EEG device to [...]

Can mRNA disrupt the drug industry?

On a brisk morning in April, dozens of investors filed into a Marriott hotel conference hall in Kendall Square, the biotech hub of Cambridge, Mass., for the first Moderna Therapeutics platform science day. They [...]

Predicting the Response to Immunotherapy Using Artificial Intelligence

VILLEJUIF, France--(BUSINESS WIRE)--A study published in The Lancet Oncology establishes for the first time that artificial intelligence can process medical images to extract biological and clinical information. By designing an algorithm and developing it [...]

#AskTheCEO Video: Cybersecurity, AI, and Industry 4.0 With Dr Johannes Drooghaag

From #AskTheCEO on YouTube: Dr. Johannes Drooghaag is the CEO of Spearhead Management, in Germany. He is an accomplished speaker in the areas of Executive Leadership, Blockchain, Artificial Intelligence, Agile Business Management. He [...]

Artificial intelligence used to predict cancer growth

Scientists have used artificial intelligence to predict how cancers will progress and evolve. This could help doctors design the most effective treatment for each patient. A team led by the Institute of Cancer Research [...]

#AskTheCEO Video: Microsoft Azure in Healthcare, and IoMT With David Houlding

From #AskTheCEO on YouTube: David Houlding is the Worldwide Healthcare Industry Leader on the Microsoft Azure Industry Experiences Team led by Paul Maher. David has more than 24 years of experience in healthcare [...]

8 ways augmented and virtual reality are changing medicine

Spine and heart surgeons will use augmented reality (AR) to simplify complex procedures. Autistic children will get relief from sensory overload with a calming virtual reality (VR) system. These and other scenarios are made [...]

The mastermind behind the first wave of surgical robots unveils the next generation

•Frederic Moll, who is known as the "Bill Gates of robotics," ushered in the first wave of surgical robotics in 1995 with his company Intuitive Surgical and its Da Vinci systems. •He has a [...]

Is Blockchain The Answer To A Better Healthcare Industry?

Data breaches are the nightmare of every major industry. When they occur, the aftermath costs of fixing the problem can be huge. According to a global study conducted by IBM and Ponemon Institute, in [...]

Frank Boehm (NA CEO) signs with IOP for Book on Nanomedical Brain/Cloud Interface

NanoApps Medical Inc. CEO Frank Boehm has signed with IOP Publishing to produce Nanomedical Brain/Cloud Interface: Explorations and Implications - a book that will explore the notion of a nanomedically enabled Brain/Cloud Interface (B/CI). [...]

Vancouver Nanomedicine Day 2018

Vancouver Nanomedicine Day 2018 will take place on Tuesday, September 11, 2018 at the Vancouver Alpen Club. We are proud to announce that one of the pioneers of the use of nanomaterials for pulmonary fibrosis, Dr. [...]

Texas A&M Team Develops New Way to Grow Blood Vessels

Formation of new blood vessels, a process also known as angiogenesis, is one of the major clinical challenges in wound healing and tissue implants. To address this issue, researchers from Texas A&M University have [...]

Landmark FDA Approval Brings Powerful Gene Silencing Method to Market

Earlier this month, the FDA approved an entirely new family of drugs, one so powerful that it could put CRISPR-based gene therapy to shame. Backed by two decades of research and a Nobel Prize, [...]

How New Technologies Could Transform Africa’s Health Care System

In early June, at the invitation of the European Commission to Brussels (Belgium), I toured some fascinating AI and blockchain-based projects, which the Commission is funding. Across industrial sectors, from healthcare to energy, from [...]

Nanorobots For Senescent Cell Clearance

One extremely promising and emerging field of research is nano-biotechnology. Nano-biotechnology could potentially be an extremely powerful tool in our quest for a longer, healthier life. Senescent cells are known to be essential in [...]

Hacking the Human Is the Next Cyber Threat

Medical technologies such as electronic devices implanted or injected into the human body are the next growth area for hackers pursuing money or control of individual people. With nanotechnology implants already being used for [...]

NanoApps Medical Near-Term Projects

NanoApps Medical is investigating the possibility that superparamagnetic nanoparticles (SPIONs) and other classes of nanoparticles (e.g., gold coated nanoshells) might have the capacity to target cancerous tumors, metastasizing cancer cells, pathogens, etc. to deactivate/eliminate [...]

‘Please do not switch me off!’ People heed begging robot

If a little humanoid robot begged you to not shut it off, would you show compassion? In an experiment designed to investigate how people treat robots when they act like humans, many participants struggled [...]

 

 

 

 

 

2018-03-22T14:37:02+00:00

Leave A Comment