New Nanoparticles Used to Detect Excessive Scarring of Wounds

Clinicians presently find it hard to predict how scars will form after surgery or after a burn wound, without using invasive testing.

The research team used new nanoparticles in animals and human skin samples to demonstrate the potential to rapidly and accurately predict whether a wound is likely to result in excessive scarring as occurs in skin contractures and keloids.

If required, doctors can then take conventional preventive steps to lessen scar formation, such as using silicon sheets to ensure a wound is flat and moist.
In developed countries alone, around 100 million patients will develop scars each year, arising from 80 million elective and trauma surgery operations. In Singapore, an estimated 400,000 people (1 in 12 people going through procedures) develop scars each year because of surgery.

Excessive scarring can greatly affect a patient’s quality of life, both psychologically and physically, as the scars can inhibit activity and movement, and can be painful when strained.

The new method was formulated by a team led by Assistant Professor Xu Chenjie from NTU’s School of Chemical and Biomedical Engineering, nanoscience expert Professor Chad A Mirkin from Northwestern University, United States, and Dr Amy S Paller, Chair of Dermatology at Northwestern University Feinberg School of Medicine.


Image Credit:  NTU Singapore

News This Week

An AI strategy is no longer optional

At the New York Times DealBook conference, Intel emphasized it was urgent that every company put an artificial intelligence (AI) strategy in place. The reason, in a word, is data. The data deluge continues [...]

Artificial synapses made from nanowires

Scientists from Jülich together with colleagues from Aachen and Turin have produced a memristive element made from nanowires that functions in much the same way as a biological nerve cell. The component is able [...]

Updated – NanoApps Medical Inc. Near-Term Projects

NanoApps Medical is investigating the possibility that superparamagnetic nanoparticles (SPIONs) (Figure 1) and other classes of nanoparticles (e.g., gold coated nanoshells) (Figure 2) might have the capacity to target cancerous tumors, metastasizing cancer cells, [...]


Leave A Comment