The earliest mention of nanotechnology and nanomedicine is ascribed to Dr. Richard Feynman in his 1959 talk at Caltech entitled “There’s Plenty of Room at the Bottom”, during which he proposed that we might manufacture progressivelysmaller machines, and in the medical realm, “swallow the surgeon.”  Nanotechnology was popularized by Dr. Eric Drexler’s in 1986 via his visionary book entitled Engines of Creation wherein he describes the almost limitless applications and potential disruptive power of nanotechnology. Drexler went on to pragmatically articulate the possibility of molecular machine systems in Nanosystems: Molecular Machinery, Manufacturing, and Computation , and further, how the advent of mature molecular manufacturing, by which practically any product may be fabricated from the bottom up, with atomic precision, might give rise to Radical Abundance.”

Nanotechnology refers to the capacity for the controllable manipulation of matter at the molecular and atomic levels toward the synthesis of unique materials, and for the creation of myriad useful devices and other products that exhibit extraordinary attributes with superior functionality. Nanotechnology is also fundamentally enabling; thus it will have strong potential to initiate significantly positive paradigm shifts across virtually every sector of society. The above said, we must be mindful as with any potentially very powerful technology, that stringent safeguards, testing standards, and comprehensive assessments of the physiological, biological, and environmental fates of the nanomaterials and processes involved, must be designed and implemented toward its development.

There are currently over 1,600 nanotechnology based consumer products already on the market. These range from the integration of nanoparticles into cosmetics and sunscreens (to enhance their appearance or performance) to spray on superhydrophobic treatments (which combine microscopic and nanometric bumps) based on the Lotus Effect whereby water droplets and any dirt always sit above the surface, meaning that the surface never actually gets wet.  A clear illustration of this is provided the company NeverWet by who makes a spray on superhydrophobic treatment for textiles and other surfaces. Other nanotechnological applications are applied to the enhancement and texture of foods and the taste of beverages through the use of nanoscale colloids and emulsions.

One of the most significant and important facets of nanotechnology will likely be its application to medicine, or what is called nanomedicine. Progressively rapid and exciting advances within this discipline are occurring globally, which hold great promise for the initiation of positive paradigm shifts across multiple medical domains. There is a powerful and quickly increasing trend toward the emergence of more compact, minimally invasive, smarter, more precise, and efficacious medical technologies.  Nanomedical diagnostics and therapeutics operate at the cellular, organellar, and molecular levels; precisely where many disease processes have their genesis, and from which they emanate. Hence, nanomedicine has strong potential for the accurate preemptive diagnoses and treatment of many diseases, prior to their having the opportunity to proliferate.

 

News

Nanoparticles could allow for faster, better medicine

November 21st, 2017|0 Comments

Gold nanoparticles could help make drugs act more quickly and effectively, according to new research conducted at Binghamton University, State University of New York. Nanoparticles are microscopic particles that are bigger than atoms but smaller [...]

Breakthrough discovery in diagnostic tools that can replace commonly used and fragile antibodies

November 20th, 2017|0 Comments

Experts from the Biotechnology Group at the University of Leicester led by Professor Sergey Piletsky in collaboration with the spin-off company MIP Diagnostics Ltd have announced the development of polymeric materials with molecular recognition capabilities [...]

Breakthrough could launch organic electronics beyond cell phone screens

November 19th, 2017|0 Comments

A discovery by an international team of researchers from Princeton University, the Georgia Institute of Technology and Humboldt University in Berlin points the way to more widespread use of an advanced technology generally known as [...]

Nanowired Drugs for Treating Alzheimer’s and Parkinson’s Diseases

November 18th, 2017|0 Comments

Millions of Americans suffer from neurodegenerative diseases such as Parkinson’s and Alzheimer’s. Researchers have identified new treatments, such as cerebrolysin, which are promising, but present clinical approaches are ineffective as critical concentrations of the drug [...]

Nanotechnology might help farmers fight climate change, pests and disease–and boost yields

November 17th, 2017|0 Comments

The sun is strong, the sky Hollywood-set blue, but the wind is brutal. This is confounding the work of Wade Elmer, chief scientist for the Department of Plant Pathology and Ecology at the Connecticut Agricultural [...]

New Study Highlights Bone-Targeted Nanoparticle Treatment for Prostate Cancer

November 16th, 2017|0 Comments

In certain patients, castrate-resistant or metastatic prostate cancer can spread to the bone. Although many new treatments are available, they can have a hard time reaching the bone and frequently result in missing the metastatic [...]

Next-generation optogenetic molecules control single neurons

November 15th, 2017|0 Comments

Researchers at MIT and Paris Descartes University have developed a new optogenetic technique that sculpts light to target individual cells bearing engineered light-sensitive molecules, so that individual neurons can be precisely stimulated. Until now, it [...]

Zipping DNA

November 14th, 2017|0 Comments

What do you do if you have a large document or a high-resolution image that is too big to send via email? You simply zip it to a more manageable size using a suitable software. [...]

Nanoparticles can limit inflammation by distracting the immune system

November 13th, 2017|0 Comments

A surprise finding suggests that an injection of nanoparticles may be able to help fight the immune system when it goes haywire, researchers at the University of Michigan have shown (ACS Nano, "Neutrophil-particle interactions in [...]

New Research on Nanotechnology Drug Delivery Market: Studying Influencing Factors and Key Players

November 12th, 2017|0 Comments

Nanotechnology Drug Delivery mainly used in healthcare applications such as such as neurology, anti-infective, cardiovascular disorders, and others. They are part of active application of the transport drugs to the final location of therapeutic intervention [...]

Researchers Develop Polymer Nanoagents to Light Up Tiny Areas of Diseased Tissues

November 11th, 2017|0 Comments

Polymer nanoagents capable of ‘lighting up’ small areas of diseased tissues that standard methods fail to detect, have been developed by a research team headed by Nanyang Technological University, Singapore (NTU Singapore). The nanoagents, called [...]

Scientists create ‘tracking’ nanoagents to illuminate very small diseased tissues

November 10th, 2017|0 Comments

Polymer nanoagents that can 'light up' tiny areas of diseased tissues that conventional methods fail to detect, have been created by a research team led by Nanyang Technological University, Singapore (NTU Singapore) The nanoagents, known [...]

Nanoshells could deliver more chemo with fewer side effects

November 9th, 2017|0 Comments

Researchers investigating ways to deliver high doses of cancer-killing drugs inside tumors have shown they can use a laser and light-activated gold nanoparticles to remotely trigger the release of approved cancer drugs inside cancer cells [...]

Nanomedicine Researchers Discover New Use for 70-Year-Old Drug

November 8th, 2017|0 Comments

A recent study reveals that a 70-year-old malaria drug is capable of blocking immune cells in the liver allowing the arrival of nanoparticles at their intended tumor site, thus overcoming a major obstacle of targeted [...]

Potential new treatment for Fragile X targets one gene to affect many

November 7th, 2017|0 Comments

In Fragile X Syndrome–the leading genetic form of intellectual disability and autism–the effects of a single defective gene ripple through a series of chemical pathways, altering signals between brain cells. It’s a complex condition, but [...]

New Nanoscale Optical ‘Abacus’ Uses Light Signals to Perform Arithmetic Computations

November 5th, 2017|0 Comments

One of the most rudimentary methods of counting has received a 21st century make-over due to the quest for developing more powerful and ever-faster computers. A global team of Researchers, including Professor C. David Wright [...]

Nano-sized gold particles have been shaped to behave as clones in biomedicine

November 4th, 2017|0 Comments

Shaping nanometric gold particles - of the size of millionths of a millimeter - to improve their properties in biomedicine and photonics has been made possible thanks to a special laser system in a work [...]

Nature Inspires Non-spherical Drug Delivery Nanoparticles

November 3rd, 2017|0 Comments

When a drug enters the body, it doesn’t generally target a particular part of the body. Paracetamol, for example, affects the whole body but its effects are felt at the source of pain. Likewise, cancer [...]

Plastic nanoparticles inspired by nature could improve cancer drug delivery

November 2nd, 2017|0 Comments

UNSW Sydney scientists have developed a way to control the shape of polymer molecules so they self-assemble into non-spherical nanoparticles - an advance that could improve the delivery of toxic drugs to tumours. "Very little [...]

Isocitrate dehydrogenases in physiology and cancer: biochemical and molecular insight

October 31st, 2017|0 Comments

From the abstract: Isocitrate dehydrogenases play important roles in cellular metabolism and cancer. This review will discuss how the roles of isoforms 1 and 2 in normal cell and cancer metabolism are distinct from those [...]

Newly patented formulation based on nanotechnology will offer neuropathic pain relief

October 30th, 2017|0 Comments

The company GB Sciences Inc. has obtained the exclusive global worldwide intellectual property license for this innovative solution, which is based on nanotechnology. The researchers Lucía Martín Banderas and Mercedes Fernández Arévalo, from the I+DNanomed [...]

Graphene sensors detect HIV DNA

October 28th, 2017|0 Comments

Leiden and Jülich researchers discovered an elegant and simple approach to improve the sensitivity of graphene biosensors. These so-called 'next generation graphene electronic biochemical sensor devices' are able to detect very low amounts of HIV [...]

Nanoparticles with pulse laser controlled antibacterial properties

October 27th, 2017|0 Comments

Silver nanoparticles (AgNPs) are known to have excellent antibacterial properties and are considered by many to be a strong contender in the critical search for an answer to antibiotic-resistant bacteria. They block enzymes and can [...]

Nanomedicine – despite the issues it still faces, investment is set to increase

October 26th, 2017|0 Comments

The nanomedicines market is worth billions and, despite a variety of hurdles, it continues to attract the attention of venture capitalists. Tarun Pandotra reviews developments in the sector. Nanotechnology has come a long way in [...]

Nanodiamonds Successfully Used in Aiding Recovery from Root Canal Procedure

October 25th, 2017|0 Comments

Root canal treatment may soon be more effective because of a miniature but powerful ally that could inhibit infection after treatment. A team of Researchers at the UCLA School of Dentistry and the UCLA Henry [...]

New Intelligent Nanoparticles Capable of Killing Cancerous Cells

October 25th, 2017|0 Comments

University of Surrey scientists have developed ‘intelligent’ nanoparticles capable of heating up to a temperature that is high enough to kill cancerous cells – but which can self-regulate and lose heat before they get hot [...]

Single nanoparticle mapping paves the way for better nanotechnology

October 24th, 2017|0 Comments

Researchers at Chalmers University of Technology and the Technical University of Denmark have developed a method that makes it possible to map the individual responses of nanoparticles in different situations and contexts. The results pave [...]

Scientists use supercomputer to search for “memory molecules”

October 23rd, 2017|0 Comments

Until now, searching for genes related to memory capacity has been comparable to seeking out the proverbial "needle in a haystack." Scientists at the University of Basel made use of the CSCS supercomputer Piz Daint [...]

Can nanotechnology heal scar tissue?

October 22nd, 2017|0 Comments

Dr Tristan Clemons, a UWA researcher, does his work on this minute scale. And while working on the nanoscale is pushing our science and technology to its limits, it's on this tiny new frontier that [...]

Safety Requirements in Nanomedicine – Video from CLINAM 2017

October 21st, 2017|0 Comments

  Robert E. Geertsma, M.Sc., Senior Scientist, Centre for Health Protection RIVM ‐ National Institute for Public Health and the Environment, Bilthoven (NL) talks at the Clinam Summit in 2017 about safety considerations [...]