From AZoNano:
Annually, dengue fever affects over 350 million people in more than 120 countries. The symptoms can range from a skin rash and achy muscles to critical hemorrhagic fever.
Scientists have found it challenging to develop effective vaccines to fight the dengue virus, partially due to the four distinct serotypes, or strains that cause the disease, as a vaccine will have to immunize against all four independently.
A new type of nanoparticle, illustrated in PLOS Neglected Tropical Diseases, has effectively vaccinated mice against one of the serotypes, and could be developed to target all four.
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